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Targeted antigen receptor treatment of cancer

Funding type: program
Funder scheme: P01
Start date: 1982-07-01
End date: 2011-06-30
Investigator: DAVID A SCHEINBERG
Institution: SLOAN-KETTERING INST CAN RESEARCH
Funded outputs count: 278
Funder award ID: P01CA033049
OpenAlex ID: G2900738668
Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response
2023 · Claire M. Storey, Mohamed Altai, et al. · Molecular Cancer Research · 3
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Treatment of Patients with Acute Myeloid Leukemia with the Targeted Alpha-Particle Nanogenerator Actinium-225-Lintuzumab
2022 · Todd L. Rosenblat, Michael R. McDevitt, et al. · Clinical Cancer Research · 70
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PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates
2021 · Darren R. Veach, Claire M. Storey, et al. · Clinical Cancer Research · 24
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Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy
2020 · Mesude Bicak, Katharina Lückerath, et al. · Proceedings of the National Academy of Sciences · 28
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Identification of the Targets of T-cell Receptor Therapeutic Agents and Cells by Use of a High-Throughput Genetic Platform
2020 · Ron S. Gejman, Heather F. Jones, et al. · Cancer Immunology Research · 43
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In vitro assays for effector T cell functions and activity of immunomodulatory antibodies
2020 · Roberta Zappasodi, Sadna Budhu, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 19
ALK and RET Inhibitors Promote HLA Class I Antigen Presentation and Unmask New Antigens within the Tumor Immunopeptidome
2019 · Claire Y. Oh, Martin G. Klatt, et al. · Cancer Immunology Research · 50
Targeted Alpha-Particle Therapy for Hematologic Malignancies
2019 · Joseph G. Jurcic · Journal of medical imaging and radiation sciences · 27
One checkpoint may hide another: inhibiting the TGFβ signaling pathway enhances immune checkpoint blockade
2019 · Aditi Gupta, Sadna Budhu, et al. · HepatoBiliary Surgery and Nutrition · 8
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Pharmacokinetics and Biodistribution of a [89Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients
2019 · Joseph A. O’Donoghue, Daniel C. Danila, et al. · Molecular Pharmaceutics · 34
Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody
2019 · Tao Dao, Sung Soo Mun, et al. · OncoImmunology · 25
ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts
2018 · Sarah M. Cheal, Shutian Ruan, et al. · Molecular Pharmaceutics · 4
Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer
2018 · Michael R. McDevitt, Daniel L. J. Thorek, et al. · Nature Communications · 62
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A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies
2017 · E Casey, S Bournazos, et al. · Leukemia · 19
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment
2017 · Sadna Budhu, David A. Schaer, et al. · Science Signaling · 144
Carbon nanotubes exhibit fibrillar pharmacology in primates
2017 · Simone Alidori, Daniel L. J. Thorek, et al. · PLoS ONE · 26
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CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes
2017 · M D Mathias, J T Sockolosky, et al. · Leukemia · 13
Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation
2017 · Daniela Weber, Robert R. Jenq, et al. · Transplantation and Cellular Therapy · 246
Advances in the clinical translation of nanotechnology
2017 · David A Scheinberg, Jan Grimm, et al. · Current Opinion in Biotechnology · 41
Deconvoluting hepatic processing of carbon nanotubes
2016 · Simone Alidori, Robert L. Bowman, et al. · Nature Communications · 52
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Opportunities and challenges for TCR mimic antibodies in cancer therapy
2016 · Aaron Y. Chang, Ron S. Gejman, et al. · Expert Opinion on Biological Therapy · 63
Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury
2016 · Simone Alidori, Nima Akhavein, et al. · Science Translational Medicine · 127
PET-based compartmental modeling of 124I-A33 antibody: quantitative characterization of patient-specific tumor targeting in colorectal cancer
2015 · Pat Zanzonico, Jorge A. Carrasquillo, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 15
Dialytic Separation of Bundled, Functionalized Carbon Nanotubes from Carbonaceous Impurities
2014 · J. Mulvey, Evan Feinberg, et al. · Crystals · 1
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Autophagy Gene Atg16l1 Prevents Lethal T Cell Alloreactivity Mediated by Dendritic Cells
2014 · Vanessa M. Hubbard-Lucey, Yusuke Shono, et al. · Immunity · 102
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