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Msc调控足细胞功能治疗狼疮性肾炎的机制研究

Amount: ¥3,000,000
Funding type: research
Funder scheme: 重点项目
Start date: 2019-01-01
End date: 2024-12-31
Investigator: 凌云 孙
Institution: 南京大学
Funded outputs count: 63
Funder award ID: 81930043
OpenAlex ID: G1600681384
Nanomaterial-based therapeutic strategies for systemic autoimmune rheumatic diseases: from molecular mechanisms to preclinical translation
2026 · Honghao Guo, Wang Xiang, et al. · Frontiers in Immunology
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Disease-specific heterogeneity of C-reactive protein across 21 hematologic disorders reflects divergent inflammatory and hematopoietic phenotypes
2026 · Honghao Guo, Jiale Zhou, et al. · Frontiers in Immunology
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PTX3 in rheumatic and autoimmune diseases: Pathogenesis, biomarker potential, and therapeutic implications
2026 · Honghao Guo, Wenwei Liu, et al. · Journal of Autoimmunity
Iron metabolism and ferroptosis in cardiovascular diseases: progress in the mechanism and pharmacological intervention
2026 · Yi Jiang, Jing Zhang, et al. · Redox Biology · 1
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Efficacy and safety of mesenchymal stem cell transplantation for progressive multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials with clinical implications for patient stratification and treatment optimization
2026 · Honghao Guo, Liuting Zeng, et al. · Frontiers in Immunology
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Expression characteristics of C-reactive protein in autoimmune diseases and their complications
2026 · Qianyue Yang, Yanfang Luo, et al. · Frontiers in Immunology · 1
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MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution
2025 · Dandan Wang, Xiang Fang, et al. · Nature Communications
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Artemisinin derivatives modulate KEAP1-NRF2-xCT pathway to alleviate Sjögren’s disease: insights from scRNA-seq and systems biology
2025 · Yong Luo, Liuting Zeng, et al. · Frontiers in Immunology · 4
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Genetically engineered MSC vesicles encapsulated with dual-gene siRNAs integrated peptide dendrimer nanoplatform for rheumatoid arthritis treatment
2025 · Min Nie, Danqing Huang, et al. · Chemical Engineering Journal
hUC-MSCs exosomes-loaded hydrogels for systemic lupus erythematosus wound treatment
2025 · Defang Meng, Danqing Huang, et al. · Chemical Engineering Journal · 2
Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus
2025 · Haiwei Zhang, Hui Yang, et al. · Lupus Science & Medicine · 4
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Allogeneic CD19-targeted CAR-T therapy in refractory systemic lupus erythematosus achieved durable remission
2025 · Dandan Wang, Xiaobing Wang, et al. · Med · 46
Mesenchymal stromal cells reduce ferroptosis of podocytes by activating the Nrf2/HO-1/GPX4 pathway in lupus nephritis
2025 · Chang Liu, Xuanqi Liu, et al. · International Immunopharmacology · 12
Efficacy and safety of mesenchymal stromal cell transplantation in the treatment of autoimmune and rheumatic immune diseases: a systematic review and meta-analysis of randomized controlled trials
2025 · Liuting Zeng, Chang Liu, et al. · Stem Cell Research & Therapy · 36
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Advances in chimeric antigen receptor T cell therapy for autoimmune and autoinflammatory diseases and their complications
2024 · Liuting Zeng, Yan Li, et al. · Journal of Autoimmunity · 10
Renal remodeling by CXCL10-CXCR3 axis-recruited mesenchymal stem cells and subsequent IL4I1 secretion in lupus nephritis
2024 · Qixiang Zhang, Yunlong Shan, et al. · Signal Transduction and Targeted Therapy · 25
Spatiotemporal piezoelectric microcapsules for programmable sonodynamic sterilization and wound healing
2024 · Danqing Huang, Min Nie, et al. · Chemical Engineering Journal · 18
Dexamethasone loaded DNA scavenger nanogel for systemic lupus erythematosus treatment
2024 · Haofang Zhu, Danqing Huang, et al. · Bioactive Materials · 20
Telitacicept: A novel horizon in targeting autoimmunity and rheumatic diseases
2024 · Liuting Zeng, Kailin Yang, et al. · Journal of Autoimmunity · 55
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases
2024 · Liuting Zeng, Kailin Yang, et al. · Cell Death and Disease · 59
Curcumin attenuates lupus nephritis by inhibiting neutrophil migration via PI3K/AKT/NF-κB signalling pathway
2024 · Hui Yang, Haiwei Zhang, et al. · Lupus Science & Medicine · 33
Efficacy and safety of culture-expanded mesenchymal stromal cell therapy in the treatment of 4 types of inflammatory arthritis: A systematic review and meta-analysis of 36 randomized controlled trials
2024 · Liuting Zeng, Kailin Yang, et al. · Seminars in Arthritis and Rheumatism · 8
Bio-Inspired Screwed Conduits from the Microfluidic Rope-Coiling Effect for Microvessels and Bronchioles
2024 · Rui Liu, Jiahui Guo, et al. · Engineering · 6
Viral Mimicking Polyplexes as Hierarchical Unpacking Vectors for Rheumatoid Arthritis Treatment
2024 · Haofang Zhu, Danqing Huang, et al. · Advanced Science · 5
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms
2024 · Wenjuan Ma, Junyi Che, et al. · ACS Nano · 27
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