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Aifa‐2016‐02364887

Funded outputs count: 30
Funder award ID: AIFA‐2016‐02364887
OpenAlex ID: G1606888652
Therapeutic Relevance of Inducing Autophagy in β-Thalassemia
2024 · Roberto Gambari, Alessia Finotti · Cells · 4
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Increased Expression of α-Hemoglobin Stabilizing Protein (AHSP) mRNA in Erythroid Precursor Cells Isolated from β-Thalassemia Patients Treated with Sirolimus (Rapamycin)
2024 · Matteo Zurlo, Cristina Zuccato, et al. · Journal of Clinical Medicine · 6
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Pharmacogenomics of Drugs Used in β-Thalassemia and Sickle-Cell Disease: From Basic Research to Clinical Applications
2024 · Roberto Gambari, Aliyu Dahiru Waziri, et al. · International Journal of Molecular Sciences · 21
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Impact of α-Globin Gene Expression and α-Globin Modifiers on the Phenotype of β-Thalassemia and Other Hemoglobinopathies: Implications for Patient Management
2024 · Joanne Traeger-Synodinos, Christina Vrettou, et al. · International Journal of Molecular Sciences · 14
New Synthetic Isoxazole Derivatives Acting as Potent Inducers of Fetal Hemoglobin in Erythroid Precursor Cells Isolated from β-Thalassemic Patients
2023 · Cristina Zuccato, Lucia Carmela Cosenza, et al. · Molecules · 5
Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences
2023 · Alessia Finotti, Jessica Gasparello, et al. · Genes · 2
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Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus
2023 · Matteo Zurlo, Cristina Zuccato, et al. · International Journal of Molecular Sciences · 9
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The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathies
2023 · Roberto Gambari, Cristina Zuccato, et al. · Biology · 11
Combined approaches for increasing fetal hemoglobin (HbF) and de novo production of adult hemoglobin (HbA) in erythroid cells from β-thalassemia patients: treatment with HbF inducers and CRISPR-Cas9 based genome editing
2023 · Alessia Finotti, Roberto Gambari · Frontiers in Genome Editing · 13
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Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study
2023 · Maria Rita Gamberini, Cristina Zuccato, et al. · Hematology Reports
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5613423 TREATMENT OF ERYTHROID PRECURSOR CELLS FROM β-THALASSEMIC PATIENTS WITH ISOXAZOLE DERIVATIVES: POTENT INDUCTION OF FETAL HEMOGLOBIN
2023 · C.Z. Cristina Zuccato, L.C.C. Lucia Carmela Cosenza, et al. · HemaSphere
5613417 Co-treatment of Erythroid Cells Isolated From Β039-thalassemia Patients With Crispr-cas9 Gene Editing and Fetal Hemoglobin Induction
2023 · M.L.P. Lipucci di Paola, L.C.C. Lucia Carmela Cosenza, et al. · HemaSphere · 1
5613260 a Phase -- Iia-iib, Open Label, Single Center Trial to Study Safety, Tolerability and Efficacy of Memantine as Supportive Long-term Treatment of Sickle Cell Patients: Trial Design and Enrollment
2023 · C.L. Levin, A.K. Koren, et al. · HemaSphere
5612976 First Administration of Hypoxic Blood in a Transfusion-dependent Patient
2023 · H. Reikvam, G. Hetland, et al. · HemaSphere
5595818 Assessment of Hematological Parameters of Petrol Filling Workers at Petrol Stations in Gondar Town, Northwest Ethiopia: a Comparative Cross-sectional Study
2023 · S.G. Sisay Getu, E.S. Elias Shiferaw, et al. · HemaSphere
Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy
2023 · Matteo Zurlo, Jessica Gasparello, et al. · Genes · 6
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Effects of Sirolimus treatment on patients with β‐Thalassemia : Lymphocyte immunophenotype and biological activity of memory CD4 + and CD8 + T cells
2023 · Matteo Zurlo, Francesco Nicoli, et al. · Journal of Cellular and Molecular Medicine · 11
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The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers
2023 · Cristina Zuccato, Lucia Carmela Cosenza, et al. · International Journal of Molecular Sciences · 7
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Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin
2022 · Lucia Carmela Cosenza, Cristina Zuccato, et al. · Genes · 8
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A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
2022 · Marco Prosdocimi, Cristina Zuccato, et al. · Wellcome Open Research · 14
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
2022 · Marco Prosdocimi, Cristina Zuccato, et al. · Wellcome Open Research · 2
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A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
2022 · Marco Prosdocimi, Cristina Zuccato, et al. · Wellcome Open Research · 8
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Droplet Digital PCR for Non-Invasive Prenatal Detection of Fetal Single-Gene Point Mutations in Maternal Plasma
2022 · Elisabetta D’Aversa, Giulia Breveglieri, et al. · International Journal of Molecular Sciences · 32
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Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective
2022 · Matteo Zurlo, Francesco Nicoli, et al. · International Journal of Molecular Medicine · 6
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Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin)
2022 · Cristina Zuccato, Lucia Carmela Cosenza, et al. · Therapeutic Advances in Hematology · 36
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