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101070950
Funder:
HORIZON EUROPE Framework Programme
Funded outputs count:
6
Funder award ID:
101070950
OpenAlex ID:
G1677613914
Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging
2026
·
Alessia Oppezzo
, Sara Sepe
, et al.
·
Nature Aging
·
3
PDF
Selection of human hematopoietic stem cells bearing the intended functional edit by transient AND-gate reporters
2026
·
Daniele Canarutto
, Martina Fiumara
, et al.
·
Nature Biotechnology
·
5
Ex vivo expansion of hematopoietic stem and progenitor cells from human mobilized peripheral blood for gene therapy applications
2026
·
Erika Zonari
, Matteo Maria Naldini
, et al.
·
Molecular Therapy
·
1
Nanoengineered 3D culture substrate enables superior persistence and polyclonal engraftment of genetically engineered hematopoietic stem cells
2026
·
Federico Midena
, Laura Alessandrini
, et al.
·
Cell stem cell
·
3
Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells
2025
·
Anastasia Conti
, Kety Giannetti
, et al.
·
Cell Reports Medicine
·
19
PDF
A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
2024
·
Lucrezia della Volpe
, Federico Midena
, et al.
·
Cell Reports Medicine
·
24
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