Human tissue specific age-related gene expression changes, their genetic regulations and the link to human diseases
Description: Narrative Leveraging existing large scale human data provides an economic, time-efficient way of performing human aging research. We plan to perform deep analyses on GTEx data to help us to better understand human tissue-specific aging, synchronized aging among tissues, and genetic regulation of aging genes. This work will significantly contribute to human aging research and establish the pre-requisite work for systems modeling of human aging.
Funder: National Institutes of Health
Amount: $370,700
Funding type: research
Funder scheme: R01
Start date: 2017-12-01
End date: 2023-11-30
Investigator: ZHIDONG TU
Institution: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Subfield: Aging
Domain: Life Sciences
Funded outputs count: 20
Funder award ID: 5r01ag055501-05
OpenAlex ID: G181234129