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Extramural Research Facilitieis Construction

Amount: $2,000,000
Funding type: grant
Funder scheme: C06
Start date: 2002-02-01
End date: 2007-01-31
Investigator: JOHN R RAYMOND
Institution: MEDICAL UNIVERSITY OF SOUTH CAROLINA
Funded outputs count: 588
Funder award ID: 1c06rr015455-01a1
OpenAlex ID: G1815537709
Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program
2026 · Swagata Goswami, Qiming Zhang, et al. · Science
Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC
2026 · Ozge Saatci, Burge Ulukan, et al. · Cell Reports Medicine
Lysyl oxidase drives ccRCC progression by coordinating HIF-2α transcription program with tumor microenvironment
2026 · Burge Ulukan, Ozge Saatci, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model
2026 · Shengyu Zou, Fan Wu, et al. · Sensory Neuroscience
Furosemide prevents noise-induced hearing loss and enhances the preventive effect of N-acetylcysteine
2026 · Hongguo Su, Fan Wu, et al. · Hearing Research · 2
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Diverse High-Fat Diets Drive Multi-Omic Reprogramming that Persists after Dietary Reversal
2026 · Andrew G. Van Camp, Jiwoon Park, et al. · SSRN Electronic Journal
5xFAD mutations induce hearing impairment in the Ahl-corrected 5xFAD mice
2025 · Hongguo Su, Fan Wu, et al. · Experimental Neurology · 2
Prevention of aminoglycoside-induced outer hair cell loss by silencing CaMKKβ in an acute mouse model
2025 · Fan Wu, Shan Xu, et al. · Hearing Research · 5
Phosphorylation of an RNA ‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging
2025 · Eunbyul Yeom, Hyejin Mun, et al. · Aging Cell · 8
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
2024 · Wyatt Wofford, Jisun Kim, et al. · Cell Reports · 15
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer
2024 · Ozge Saatci, Rashedul Alam, et al. · Cell Death and Disease · 36
Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors
2024 · Megan Sheridan, Nityananda Chowdhury, et al. · iScience · 9
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Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer
2024 · Mustafa Emre Gedik, Ozge Saatci, et al. · Cancer Research · 40
p17/C18-ceramide–mediated mitophagy is an endogenous neuroprotective response in preclinical and clinical brain injury
2024 · Eda Karakaya, Natalia Oleinik, et al. · PNAS Nexus · 11
The Revised Hearing Handicap Inventory and Pure-Tone Average Predict Hearing Aid Use Equally Well
2023 · Lauren K. Dillard, Lois J. Matthews, et al. · American Journal of Audiology · 11
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Adaptive changes in tumor cells in response to reductive stress
2023 · Leilei Zhang, Jie Zhang, et al. · Biochemical Pharmacology · 9
Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
2023 · Ozge Saatci, Metin Cetin, et al. · Nature Communications · 12
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Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer
2023 · Mustafa Emre Gedik, Ozge Saatci, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway
2023 · Ruosha Lai, Qiaojun Fang, et al. · Frontiers in Cellular Neuroscience · 20
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Adaptive Changes in Tumor Cells in Response to Reductive Stress
2023 · Leilei Zhang, Jie Zhang, et al. · Journal of Pharmacology and Experimental Therapeutics
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Review of the Delivery Kinetics of Thermosensitive Liposomes
2023 · Dieter Haemmerich, Krishna K. Ramajayam, et al. · Cancers · 34
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Selecting ideal drugs for encapsulation in thermosensitive liposomes and other triggered nanoparticles
2022 · Krishna K. Ramajayam, Danforth A. Newton, et al. · International Journal of Hyperthermia · 7
Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKβ
2022 · Fan Wu, Kayla Hill, et al. · Cellular and Molecular Life Sciences · 28
Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities
2022 · Anjan Motamarry, A. Marissa Wolfe, et al. · Cancers · 6
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Premarin Reduces Neurodegeneration and Promotes Improvement of Function in an Animal Model of Spinal Cord Injury
2022 · Azizul Haque, Arabinda Das, et al. · International Journal of Molecular Sciences · 11
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