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Mechanisms of inflammatory disease.

Amount: £2,640,000
Funding type: training-grant
Funder scheme: Immune System in Health and Disease
Start date: 2016-10-01
End date: 2023-09-25
Investigators: Stephen Watson, Robin May
Institution: University of Birmingham
Funded outputs count: 10
Funder award ID: 108871
OpenAlex ID: G1830233433
A minimum valency of 4 is required for robust activation of platelets in flow cytometry by multivalent nanobodies to Glycoprotein VI, C-type lectin-like receptor 2 and Platelet Endothelial Aggregation Receptor 1
2025 · Rachel E. Lamerton, Eleyna M. Martin, et al. · Research and Practice in Thrombosis and Haemostasis · 3
Platelet aggregation responses to Salmonella Typhimurium are determined by host anti- Salmonella antibody levels
2024 · Rachel E Lamerton, Samantha J Montague, et al. · Platelets · 5
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A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts
2024 · Laura Bravo, Joana FF Simões, et al. · The Lancet Digital Health · 22
SARS-CoV-2 Spike- and Nucleoprotein-Specific Antibodies Induced After Vaccination or Infection Promote Classical Complement Activation
2022 · Rachel E Lamerton, Edith Marcial Juarez, et al. · Frontiers in Immunology · 24
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Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic
2021 · Himanshi Chawla, Sian E. Jossi, et al. · Journal of Molecular Biology · 21
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The Role of B Cells in Adult and Paediatric Liver Injury
2021 · Arzoo M. Patel, Yuxin S. Liu, et al. · Frontiers in Immunology · 41
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Changes in Circadian Rhythms Dysregulate Inflammation in Ageing: Focus on Leukocyte Trafficking
2021 · Poppy Nathan, Julie Elizabeth Gibbs, et al. · Frontiers in Immunology · 33
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The Role of Protein and Lipid Clustering in Lymphocyte Activation
2021 · Rachel E. Lamerton, Abbey Lightfoot, et al. · Frontiers in Immunology · 18
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-Omics biomarker identification pipeline for translational medicine
2019 · Laura Bravo-Merodio, John A. Williams, et al. · Journal of Translational Medicine · 49
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Robust Phagocyte Recruitment Controls the Opportunistic Fungal Pathogen Mucor circinelloides in Innate Granulomas In Vivo
2018 · Sarah Inglesfield, Aleksandra Jasiulewicz, et al. · mBio · 30
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