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Understanding Alzheimer Blood Biomarkers for Tau Pathology

Description: Could better blood tests help detect Alzheimer’s early, before symptoms appear?
Funding type: research
Funder scheme: ZEN
Start date: 2021-01-01
Investigator: Kaj Blennow (lead)
Field: Medicine
Funded outputs count: 277
Funder award ID: ZEN-21-848495
OpenAlex ID: G184585344
Spatiotemporal characterization of Alzheimer disease pathology in living human brain tissue
2026 · Aram Aslanyan, Soumya Mukherjee, et al. · Nature Communications · 1
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CSF p-tau205: a biomarker of Alzheimer’s disease progression and biological staging
2026 · Juan Lantero-Rodriguez, Shorena Janelidze, et al. · Molecular Psychiatry
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Astrocyte reactivity modifies the effects of locus coeruleus norepinephrine‐related dysfunction on tau and its impact on cognition
2026 · Prokopis C. Prokopiou, Maxime Van Egroo, et al. · Alzheimer s & Dementia
Cerebrospinal fluid biomarkers reveal transdiagnostic synaptic dysfunction across major psychiatric disorders
2026 · Andreas Göteson, Johanna Nilsson, et al. · Nature Communications · 1
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Spatiotemporal dynamics of tau extent and load increase in Alzheimer’s disease across four longitudinal cohorts
2026 · Arthur C. Macedo, Lydia Trudel, et al. · Nature Aging · 10
Performance of Alzheimer Disease Plasma Biomarkers in Patients With Prion Diseases
2026 · Thomas Coysh, Rhiannon Laban, et al. · Neurology · 2
Neurofilament light chain and glial fibrillary acidic protein as biomarkers of peripheral nervous system involvement in multiple sclerosis: diagnostic and prognostic evaluation
2026 · Alina Flintere-Flinte, Vladimirs Krutovs, et al. · BMC Neurology
GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy
2026 · Jigyasha Timsina, Chenyang Jiang, et al. · Nature Communications · 6
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Cerebrospinal fluid and frontal cortex TMPRSS2 and ACE2 protein levels differ in Down syndrome and Alzheimer’s disease
2026 · Carlos Avilés-Granados, Adriana Gea-González, et al. · Acta Neuropathologica Communications
Metabolic and renal factors associated with plasma phosphorylated tau analytes used to detect Alzheimer's disease pathology
2026 · Kao Lee Yang, Yue Ma, et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · 2
Cerebrospinal fluid NPTX2/p‐tau ratio as a biomarker for cognitive decline in neurodegenerative diseases
2026 · Bárbara Fernandes Gomes, Mathias Sauer, et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · 1
Selective reduction of ADAM10 in brain and cerebrospinal fluid of Alzheimer’s disease patients
2026 · Adriana Gea-González, Renata Valle-Pedroso, et al. · Alzheimer s Research & Therapy · 1
Aβ-related Cerebrospinal Fluid Proteins in Alzheimer’s Disease Reflect Gene Expression Levels Found in The Healthy Cortex
2026 · Pedro Rosa-Neto, Seyyed Ali Hosseini, et al. · Research Square
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Physical activity across the life course and neural biomarkers
2026 · Elisa R. Torres, Eloise D. Lopez, et al. · Journal of Alzheimer s Disease
Biomarker-integrated prognostic stagings for Alzheimer’s Disease
2026 · Daeun Shin, Sungjoo Lee, et al. · Nature Communications · 6
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Plasma Phosphorylated Tau 217 Cutoffs for Amyloid Pathology and Kidney Function, Body Mass Index, and Anemia
2026 · Jihwan Yun, Jungah Lee, et al. · JAMA Neurology · 18
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N‐Truncated Superoxide Dismutase‐1 in Cerebrospinal Fluid Is Folded and Active
2026 · Laura Leykam, Karin M. E. Forsberg, et al. · Journal of Neurochemistry
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Glymphatic dysfunction links vascular pathology to Alzheimer’s biomarkers and cognitive decline
2026 · Sung Hoon Kang, Seongmi Kim, et al. · Alzheimer s Research & Therapy · 9
Early functional changes and plasma GFAP in Swedish families with Autosomal Dominant Alzheimer’s disease mutations
2026 · Emma S. Luckett, Mariola Zapater-Fajari, et al. · Translational Psychiatry · 1
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Cerebrospinal fluid levels of neurogranin and YKL-40 in mild cognitive impairment due to Alzheimer's disease or vascular dementia
2026 · Ulla Andin, Svante Lifvergren, et al. · Journal of Alzheimer s Disease
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology
2026 · Hanna Huber, Laia Montoliu-Gaya, et al. · Nature Medicine · 41
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Increased cerebrospinal fluid YKL-40 concentration in hip fracture patients with delirium
2026 · Thea Berntsen, Kaj Blennow, et al. · Brain Communications · 1
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Tracking clinical and neuroimaging progression of Alzheimer's disease by longitudinal trajectories of plasma biomarkers
2026 · Frederikke Kragh Clemmensen, Mathias Holsey Gramkow, et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Correlation of blood biomarkers with microstructural brain injury in survivors of out-of-hospital cardiac arrest
2026 · Mikael V Laaksonen, Jussi P Posti, et al. · Brain Communications
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Plasma p-tau212 identifies cognitively unimpaired individuals with emerging amyloid-β pathology
2025 · Przemysław R. Kac, Armand González-Escalante, et al. · Journal of Neurology · 4
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