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WT098565

Funded outputs count: 10
Funder award ID: WT098565
OpenAlex ID: G1859303785
Transposable Element Landscape in Drosophila Populations Selected for Longevity
2021 · Daniel K Fabian, Handan Melike Dönertaş, et al. · Genome Biology and Evolution · 10
From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing
2021 · Maarouf Baghdadi, Helena M Hinterding, et al. · Briefings in Functional Genomics · 9
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Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice
2021 · Matias Fuentealba, Daniel K. Fabian, et al. · Mechanisms of Ageing and Development · 11
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PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity
2020 · Yifan Yu, Teresa Niccoli, et al. · Human Molecular Genetics · 16
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Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production
2019 · Luke S. Tain, Chirag Jain, et al. · Aging Cell · 65
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Using the drug-protein interactome to identify anti-ageing compounds for humans
2019 · Matías Fuentealba Valenzuela, Handan Melike Dönertaş, et al. · PLoS Computational Biology · 45
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Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster
2018 · Hrvoje Augustin, Kieran McGourty, et al. · Neurobiology of Aging · 17
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Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies
2017 · Hrvoje Augustin, Kieran McGourty, et al. · PLoS Biology · 30
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Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease
2017 · Fiona Kerr, Oyinkan Sofola-Adesakin, et al. · PLoS Genetics · 146
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Aβ43 is neurotoxic and primes aggregation of Aβ40 in vivo
2015 · Sylvie Burnouf, Marianna Karina Gorsky, et al. · Acta Neuropathologica · 46
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