Award

Mitochondrial Protein Misfolding and Aggregation after Hypoxia: Mechanisms and Mitigation

Description: Project Narrative Hypoxic cell death in the form of stroke and myocardial infarction is the number one cause of mortality in the US. Through the research aims proposed here, new mechanisms of damage to mitochondria, the powerhouse of the cell, will be discovered and understood. Through a better understanding of mitochondrial injury, new strategies to treat stroke and myocardial infarction may emerge.
Funding type: research
Funder scheme: R01
Start date: 2017-07-15
End date: 2023-06-30
Investigator: C. MICHAEL CROWDER
Institution: UNIVERSITY OF WASHINGTON
Funded outputs count: 9
Funder award ID: R01NS100350
OpenAlex ID: G7384681148
2024 · C. Michael Crowder, Stuart A. Forman · Anesthesiology · 3
2023 · Chun-Ling Sun, Marc Van Gilst, et al. · Cell Death and Disease · 22
2020 · Omar A. Itani, Xuefei Zhong, et al. · Current Biology · 22
2017 · Daniel M Kaufman, Xia Wu, et al. · Cell Death and Differentiation · 51
2017 · Chun-Ling Sun, Huiliang Zhang, et al. · PLoS ONE · 10
Year
Topic