Award

(Attack)2: Genetic engineering of cellular and humoral immunity to cure HIV

Description: Overall: Project Narrative We propose to combine gene engineering of both arms of the adaptive immune response to provide long lasting and broad anti-HIV-1 responses that are capable of suppressing/eliminating HIV-1 replication, thereby leading to an HIV cure.
Funding type: cooperative_agreement
Funder scheme: U19
Start date: 2020-05-07
End date: 2026-04-30
Investigator: IRVIN S.Y. CHEN
Institution: UNIVERSITY OF CALIFORNIA LOS ANGELES
Funded outputs count: 23
Funder award ID: U19AI149504
OpenAlex ID: G4552839445
2025 · Wenli Mu, Shallu Tomer, et al. · The Journal of Immunology
2025 · Markus Isfeld Diehl, Nathan E. Reticker-Flynn, et al. · The Journal of Immunology · 2
2025 · Qi Guo, Keval Parikh, et al. · Molecular Therapy — Methods & Clinical Development · 3
2025 · Wenli Mu, Shallu Tomer, et al. · Journal of Clinical Investigation · 19
2024 · Kari-Ann Takano, Anita A.L. Wong, et al. · Molecular Therapy · 7
2023 · Lan Wang, Gajendra W. Suryawanshi, et al. · Heliyon · 1
2023 · Jason Murray, Teresa Einhaus, et al. · Molecular Therapy — Methods & Clinical Development · 7
2022 · Shallu Tomer, Wenli Mu, et al. · Frontiers in Immunology · 27
2022 · Gustavo Garcia, Nikhil Chakravarty, et al. · Microbiology Spectrum · 6
2021 · Christopher W. Peterson · Journal of Clinical Investigation · 6
2021 · Anjie Zhen, Mayra A. Carrillo, et al. · PLoS Pathogens · 37
2021 · Isaac M. Barber-Axthelm, Valerie Barber-Axthelm, et al. · JCI Insight · 43
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