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A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC Collaboration

Description: COSMIC is an international consortium of population-based prospective longitudinal cohorts examining the risk and protective factors and biomarkers for cognitive decline and dementia in older individuals world-wide. From the time of its initial funding in 2017, COSMIC has developed into a consortium of 54 studies from 39 countries in six continents, with a combined sample size of 175,199, and an additional 25 studies in negotiation, potentially increasing the sample to 300,000, with several strategic collaborations. With its global reach, open sharing of data and diverse network of researchers, COSMIC is creating a truly global epidemiology of dementia that is needed to meet the ambitious goals of the 2017 World Health Assembly to address the global epidemic of dementia, and the hopes of people at risk of dementia everywhere.
Funding type: research
Funder scheme: R01
Start date: 2017-09-15
End date: 2028-06-30
Investigator: PERMINDER S SACHDEV
Institution: UNIVERSITY OF NEW SOUTH WALES
Funded outputs count: 56
Funder award ID: R01AG057531
OpenAlex ID: G9000892911
2026 · Perminder S. Sachdev · Australasian Psychiatry
2026 · Olivia E. Giameos, Maddison L. Mellow, et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions
2026 · Agustina Legaz, Sebastian Moguilner, et al. · Nature Medicine · 17
2026 · Ying Xu, Perminder S. Sachdev, et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 2
2026 · Darren M. Lipnicki, Meritxell Valentí, et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
2026 · Darren M. Lipnicki, Ashleigh S. Vella, et al. · Psychiatry and Clinical Neurosciences · 2
2026 · Mai P. Ho, Nikita K. Husein, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Perminder S. Sachdev, Adam C. Bentvelzen, et al. · Journal of the American College of Cardiology · 38
2026 · Louise S. Goodall, Matthew J. Lennon, et al. · Journal of the American College of Cardiology · 12
2025 · Liliana Laranjo, Lorainne Tudor Car, et al. · The Lancet Primary Care · 16
2025 · Shizuka Hayashi, Jiyang Jiang, et al. · American Journal of Geriatric Psychiatry · 3
2025 · Dae Jong Oh, Darren M. Lipnicki, et al. · Alzheimer s & Dementia · 7
2025 · Ashleigh S. Vella, Susanne Roehr, et al. · Current Opinion in Psychiatry · 2
2025 · Susanne Röhr, Simone Reppermund, et al. · The Lancet Healthy Longevity · 6
2025 · Darren M. Lipnicki, Meritxell Valentí, et al. · medRxiv · 1
2025 · Annabel P Matison, Suraj Samtani, et al. · The Journals of Gerontology Series B · 10
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