APOE Genotype Mediated Effects on Alzheimer Disease Risk and Mechanisms
Description: NARRATIVE In this project, we will discover new genetic factors that elucidate potential mechanisms for the effects of APOE ɛ2 and ɛ4 on AD risk in multiple ethnic populations, use this information to understand how genetic variation leads to pathologic states, identify novel biomarkers, and provide models which can be used in small molecule drug screens for potential AD treatments
Funder: National Institutes of Health
Amount: $810,700
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2024-09-15
End date: 2029-06-30
Investigator: LINDSAY A. FARRER
Institution: BOSTON UNIVERSITY MEDICAL CAMPUS
Funded outputs count: 16
Funder award ID: 1u01ag082665-01a1
OpenAlex ID: G1924716505