Get started
Award

MR/K019392/1

Funded outputs count: 33
Funder award ID: MR/K019392/1
OpenAlex ID: G1930245786
Macrophages promote collagen deposition through circadian regulation of fibroblasts
2025 · Katherine Lowles, Marie F.A. Cutiongco, et al. · bioRxiv (Cold Spring Harbor Laboratory)
A synthetic chronogenetic gene circuit for programmed circadian drug delivery
2025 · Lara Pferdehirt, Anna R. Damato, et al. · Nature Communications · 20
PDF
Associations between work characteristics and osteoarthritis: A cross-sectional study of 285,947 UK Biobank participants
2025 · A. Hashmi, S. Scott, et al. · Osteoarthritis and Cartilage Open · 5
PDF
Circadian and permanent pools of extracellular matrix co-exist in tendon tissue, but have distinct rates of turnover and differential responses to ageing
2024 · Anna Hoyle, Joan Chang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
Modulation of circadian rhythms in articular cartilage by heat pulses
2024 · Cátia F. Gonçalves, Michal Dudek, et al. · bioRxiv (Cold Spring Harbor Laboratory)
PDF
Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks
2023 · Michal Dudek, Dharshika R. J. Pathiranage, et al. · Nature Communications · 44
PDF
Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts
2023 · Ching-Yan Chloé Yeung, Richa Garva, et al. · Matrix Biology · 16
Macromolecular condensation buffers intracellular water potential
2023 · Joseph L. Watson, Estere Seinkmane, et al. · Nature · 173
The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc
2023 · Michal Dudek, Honor Morris, et al. · Matrix Biology · 41
Tick tock, the cartilage clock
2023 · Natalie Rogers, Qing-Jun Meng · Osteoarthritis and Cartilage · 28
PDF
Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors
2023 · Christopher A. Smith, Paul A. Humphreys, et al. · PLoS ONE · 17
PDF
Synthetic gene circuits for preventing disruption of the circadian clock due to interleukin-1–induced inflammation
2022 · Lara Pferdehirt, Anna R. Damato, et al. · Science Advances · 39
PDF
Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration
2022 · Dong Wang, Pandi Peng, et al. · Bone Research · 52
PDF
Circadian time series proteomics reveals daily dynamics in cartilage physiology
2021 · M. Dudek, C. Angelucci, et al. · Osteoarthritis and Cartilage · 30
PDF
Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc
2021 · Honor Morris, Cátia F Gonçalves, et al. · Annals of the Rheumatic Diseases · 48
Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator
2020 · Nan Yang, Nicola J. Smyllie, et al. · PLoS Genetics · 30
PDF
Timing metabolism in cartilage and bone: links between circadian clocks and tissue homeostasis
2019 · Cátia F Gonçalves, Qing-Jun Meng · Journal of Endocrinology · 25
PDF
Influence of the extracellular matrix on cell-intrinsic circadian clocks
2019 · Charles H. Streuli, Qing-Jun Meng · Journal of Cell Science · 36
Circadian Clocks in Articular Cartilage and Bone
2016 · Nan Yang, Qing-Jun Meng · Journal of Biological Rhythms · 41
PDF
Catching the rhythm of disc degeneration
2016 · Dario Ummarino · Nature Reviews Rheumatology · 3
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
2016 · Michal Dudek, Nan Yang, et al. · Annals of the Rheumatic Diseases · 165
PDF
The brain–joint axis in osteoarthritis: nerves, circadian clocks and beyond
2016 · Francis Berenbaum, Qing-Jun Meng · Nature Reviews Rheumatology · 91
Chondrocyte clock maintains cartilage tissue
2016 · Sarah Onuora · Nature Reviews Rheumatology · 11
The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity
2015 · Michal Dudek, Nicole Gossan, et al. · Journal of Clinical Investigation · 221
PDF
Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet
2015 · Ranjan Kc, Xin Li, et al. · Scientific Reports · 34
PDF
Year
Topic