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KP1605010
Funder:
U.S. Department of Energy
Funded outputs count:
249
Funder award ID:
KP1605010
OpenAlex ID:
G2004402655
Strategy for modular assembly of tetravalent, multispecific antibodies
2026
·
Evan Mallette
, Levi L. Blazer
, et al.
·
Protein Science
PDF
A sequence motif enables widespread use of noncanonical redox cofactors in natural enzymes
2026
·
Samer Saleh
, Ning-Hsiang Hsu
, et al.
·
Nature Chemical Biology
PDF
Differential Water Networks Guide Selectivity Optimization of a Cell Active BPTF Inhibitor in Neuroblastoma
2026
·
Kesavan Babu
, Chun‐Ju Tsou
, et al.
·
Angewandte Chemie
X-ray crystallographic fragment screening reveals novel and conformationally dynamic ligand-binding sites in Mycobacterium tuberculosis FtsZ
2026
·
Kaylen R. Meeks
, Edwin O. Lazo
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Convergent strategies for nanobody-mediated inhibition of an epoxide hydrolase
2026
·
Adam R. Simard
, Noor M. Taher
, et al.
·
Journal of Structural Biology X
Isoprenoid Binding and Substrate Channeling in Drimenol Synthase, a Bifunctional Class II Terpene Cyclase-Phosphatase
2026
·
Kristin R. Osika
, Mason E. Leffler
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance
2026
·
Jianyong Liu
, Qing-Li He
, et al.
·
Nature Communications
·
5
PDF
Mechanistic Roles of Conserved Active-Site Residues in OXA-48 Carbapenem Hydrolysis
2026
·
Doris M. Taylor
, Dignité Fabrice Ngango
, et al.
·
ACS Infectious Diseases
Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors
2026
·
Yuchen Ma
, Erika McCarthy
, et al.
·
Angewandte Chemie International Edition
PDF
Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors
2026
·
Yuchen Ma
, Erika McCarthy
, et al.
·
Angewandte Chemie
Near-Adjacent Heavy Lanthanide Separation and Sensing Using Dimerizing Lanmodulins
2026
·
Wonseok Choi
, Xianxian Zhou
, et al.
·
Journal of the American Chemical Society
·
1
De novo design of autocatalytically forming intra- and intermolecular isopeptide bonds to construct rigid covalent protein assemblies
2026
·
Lukas F Milles
, Evelyn B Huddy
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Scanning X-ray microdiffraction studies of protein accumulation and tissue loss in thin sections of human brain tissue in Alzheimer’s disease
2026
·
Prakash Nepal
, Abdullah Al Bashit
, et al.
·
Scientific Reports
PDF
Colloidal Crystals Engineered with DNA and Perylenediimide Exhibit Symmetry-Breaking Charge Transfer
2026
·
Cuizheng Zhang
, Yi Xie
, et al.
·
Journal of the American Chemical Society
Robust structural, kinetic and biophysical characterization of wild-type human ACOD1, selected mutants and their interaction with citraconate
2026
·
Brent Runge
, Hande Oktay
, et al.
·
Journal of Structural Biology X
PDF
Post-loading ribonucleic acid into lipid nanoparticle carriers
2026
·
Navid Bizmark
, David F. Amelemah
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
2026
·
Hannah C. Geisler
, Hannah C. Safford
, et al.
·
Advanced Materials
Epitope-guided Detection of a Molecular Glue-induced Ternary Complex Using Engineered Synthetic Antibody Fragments
2026
·
Kelly M. O’Leary
, Tomasz Slezak
, et al.
·
Journal of Molecular Biology
PDF
Dysregulation of Human ClpP Using Small Molecules with Piperazine-Based Scaffold for Diffuse Intrinsic Pontine Glioma Therapy Validated by Patient-Derived Tumor Organoids
2026
·
Morena Miciaccia
, Domenico Armenise
, et al.
·
Journal of Medicinal Chemistry
PDF
Orally available designed miniproteins inhibit enterotoxigenic Bacteroides fragilis pathology by blocking toxin receptor binding
2026
·
Pooja Srinivas
, Victor Adebomi
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
Atg23 interacts with both the N- and C-termini of Atg9 via a hydrophobic binding pocket
2026
·
Zhanibek Bekkhozhin
, Kelsie A. Leary
, et al.
·
Journal of Biological Chemistry
·
3
EsxA is required for antibacterial toxin export by the type VIIb secretion system
2026
·
Prakhar Y. Shah
, Stephen R. Garrett
, et al.
·
Journal of Biological Chemistry
·
2
PDF
Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
2026
·
Jordan M. Mancl
, Wenguang G. Liang
, et al.
·
eLife
Dynamic Arrest and Tunable Gelation of Immunogenically Inert POEGMA Nanoparticles
2026
·
Parul Sirohi
, Max R. Ney
, et al.
·
ACS Polymers Au
Identifying a cooperative catalytic network for efficient esterase catalysis
2026
·
Sharad Sarak
, Hong Yang
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
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