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Filifactor alocis interactions with neutrophils

Description: Project Narrative Periodontitis is a chronic inflammatory disease induced by oral pathogenic bacteria that affects ~50% of the adults in the United States. Oral health status is maintained by the presence of white blood cells which are involved in killing the oral bacteria that cause periodontitis. In the current study we propose to define how a newly appreciated bacterium manages to avoid being killed by the white blood cells; with the intention of filling a significant gap in the understanding of which factors contribute to periodontal disease.
Funding type: research
Funder scheme: R01
Start date: 2014-07-01
End date: 2025-08-31
Investigator: SILVIA M URIARTE
Institution: UNIVERSITY OF LOUISVILLE
Subfield: Periodontics
Field: Dentistry
Funded outputs count: 19
Funder award ID: R01DE024509
OpenAlex ID: G2022148158
2025 · A. Vashishta, L. Li, et al. · Journal of Dental Research · 7
2025 · Zi Wang, Anish Saxena, et al. · International Journal of Oral Science · 54
2022 · Silvia M. Uriarte, George Hajishengallis · Immunological Reviews · 71
2022 · Mina M. Z. Iskander, Gwyneth J. Lamont, et al. · Journal Of Clinical Periodontology · 8
2022 · Hazel Ozuna, Ian Snider, et al. · Frontiers in Oral Health · 33
2022 · Irina Miralda, Aruna Vashishta, et al. · Molecular Microbiology · 19
2020 · Irina Miralda, Silvia M. Uriarte · Molecular Oral Microbiology · 52
2020 · Lanhai Lü, Lan Yakoumatos, et al. · The FASEB Journal · 21
2019 · Melody Y. Zeng, Irina Miralda, et al. · Molecular Oral Microbiology · 169
2018 · Jacob S. Edmisson, Shifu Tian, et al. · Cellular Microbiology · 39
2017 · Irina Miralda, Silvia M. Uriarte, et al. · Frontiers in Cellular and Infection Microbiology · 189
2016 · Cortney L. Armstrong, Irina Miralda, et al. · Infection and Immunity · 47
2016 · Silvia M. Uriarte, Jacob S. Edmisson, et al. · Immunological Reviews · 112
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