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Social Isolation and Sleep Disturance in Aging: Inflammatory Mechanisms

Description: Project Narrative Social isolation has significant health consequences in older adults, but it is not known how feelings of loneliness and loss of emotional connections lead to increases in disease risk. Given our evidence that social isolation is associated with sleep disturbance, and such sleep difficulties increase inflammation with consequences for a number of medical disorders including cardiovascular disorder, diabetes mellitus, and cancer, this study will examine the relationships between social isolation, sleep disturbance and inflammation in socially isolated older adults. This study will inform the development of potential treatments that target disordered sleep with possible prevention of disease outcomes in older adults who are socially isolated.
Funding type: research
Funder scheme: R01
Start date: 2009-09-15
End date: 2015-08-31
Investigator: MICHAEL R IRWIN
Institution: UNIVERSITY OF CALIFORNIA LOS ANGELES
Field: Psychology
Funded outputs count: 106
Funder award ID: R01AG034588
OpenAlex ID: G2553325857
2024 · Chloe C. Boyle, Steve W. Cole, et al. · Brain Behavior & Immunity - Health · 7
2024 · Ling-Ling Tao, Cai-Hua Zeng, et al. · World Journal of Clinical Cases · 3
2022 · Dominique Piber, Joshua H. Cho, et al. · Brain Behavior and Immunity · 96
2021 · Jennifer L. Kruse, Richard Olmstead, et al. · Journal of Psychiatric Research · 28
2021 · Jennifer L. Kruse, Megha M. Vasavada, et al. · Translational Psychiatry · 48
2020 · Dominique Piber, Naomi I. Eisenberger, et al. · Brain Behavior and Immunity · 13
2020 · Jennifer L. Kruse, Richard Olmstead, et al. · Brain Behavior and Immunity · 46
2019 · JOSHUA HYONG-JIN CHO, SARA M. SHU, et al. · Archives of Clinical Psychiatry (São Paulo) · 1
2019 · S. Melanie Lee, Silena Te, et al. · The World Journal of Biological Psychiatry · 7
2019 · Dominique Piber, Richard Olmstead, et al. · The Journals of Gerontology Series A · 62
2019 · Mona Moieni, Kevin M. Tan, et al. · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · 51
2018 · Jennifer L. Kruse, Eliza Congdon, et al. · The Journal of Clinical Psychiatry · 105
2016 · Michael R Irwin, Naomi I Eisenberger · Neuropsychopharmacology · 15
2016 · Michael R Irwin, Mark R Opp · Neuropsychopharmacology · 623
2016 · Naomi I Eisenberger, Mona Moieni, et al. · Neuropsychopharmacology · 398
2016 · Judith E. Carroll, Michael R. Irwin, et al. · Biological Psychiatry · 173
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