Hypoxia and inflammatory injury in human renovascular hypertension
Description: PUBLIC HEALTH RELEVANCE: These studies are relevant to prevention of progressive kidney disease, particularly in older subjects with widespread vascular disease. They will address directly evolving concepts linking large-vessel occlusive disease to inflammatory renal injury. Importantly, these studies will for the first time explore the role of mesenchymal stem cells as a means to repair tissue injury beyond an occlusive vascular lesion in humans.
Funding type: research
Funder scheme: R01
Start date: 2014-05-20
End date: 2019-04-30
Investigator: LILACH O LERMAN
Institution: MAYO CLINIC ROCHESTER
Funded outputs count: 97
Funder award ID: R01DK100081
OpenAlex ID: G1315383539