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Rg1181642744df59

Funded outputs count: 11
Funder award ID: RG1181642744DF59
OpenAlex ID: G2166913325
BACH1/HO-1 axis dysregulation links Down syndrome to Alzheimer-like neurodegeneration
2026 · Fabio Di Domenico, Eugenio Barone, et al. · Neurochemistry International
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Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome
2026 · Monika Rataj Baniowska, Paige Mumford, et al. · Alzheimer s & Dementia · 3
Loss of Proteostasis and Early-Onset Neurodegeneration in Down Syndrome: From Mechanisms to Interventions
2026 · Antonella Tramutola, Chiara Lanzillotta, et al. · Antioxidants · 2
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Systemic administration of the OGT inhibitor OSMI-1 normalizes hippocampal O-GlcNAcylation and improves recognition memory, redox balance, and brain mitochondrial homeostasis in a Rett syndrome mouse model
2025 · Chiara Sette, Chiara Urbinati, et al. · Free Radical Biology and Medicine · 4
Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers
2025 · Chiara Lanzillotta, Francesca Prestia, et al. · Redox Biology · 10
Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2
2025 · Brigitta Buttari, Antonella Tramutola, et al. · Biomolecules · 44
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Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
2023 · Marzia Perluigi, Fabio Di Domenico, et al. · Physiological Reviews · 290
High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer’s Disease Signatures
2021 · Ilaria Zuliani, Chiara Lanzillotta, et al. · International Journal of Molecular Sciences · 32
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Stress Responses in Down Syndrome Neurodegeneration: State of the Art and Therapeutic Molecules
2021 · Chiara Lanzillotta, Fabio Di Domenico · Biomolecules · 36
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The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome
2020 · Ilaria Zuliani, Chiara Lanzillotta, et al. · Neurotherapeutics · 28
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Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children
2020 · Chiara Lanzillotta, Viviana Greco, et al. · Antioxidants · 85
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