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Untersuchung der Chromosomeninstabilität, abnormaler Zellzyklus-Checkpoints, Alterung und deren Einfluss auf die Induktion von Pluripotenz

Amount: €275,400
Funding type: grant
Funder scheme: Grundlagen der regenerativen Medizin
Start date: 2010-08-01
End date: 2014-02-28
Institution: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
Funded outputs count: 15
Funder award ID: 01GN1005
OpenAlex ID: G2187257915
Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature
2019 · Lucas-Sebastian Spitzhorn, Matthias Megges, et al. · Stem Cell Research & Therapy · 141
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Transplanted Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Support Liver Regeneration in Gunn Rats
2018 · Lucas-Sebastian Spitzhorn, Claus Kordes, et al. · Stem Cells and Development · 26
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants
2017 · Barbara Mlody, Wasco Wruck, et al. · Scientific Reports · 13
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Episomal plasmid-based generation of induced pluripotent stem cells from fetal femur-derived human mesenchymal stromal cells
2015 · Matthias Megges, Richard O.C. Oreffo, et al. · Stem Cell Research · 8
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Generation of iPSC lines from primary human amniotic fluid cells
2015 · Katharina Drews, Peggy Matz, et al. · Stem Cell Research · 13
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Generation of iPSC lines from primary human chorionic villi cells
2015 · Björn Lichtner, Peggy Matz, et al. · Stem Cell Research · 1
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Generation of iPSC lines from a Nijmegen Breakage Syndrome patient
2015 · Barbara Mlody, James Adjaye · Stem Cell Research · 6
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Generation of iPSC line epiHUVEC from human umbilical vein endothelial cells
2015 · Peggy Matz, James Adjaye · Stem Cell Research · 8
Generation of an iPS cell line from bone marrow derived mesenchymal stromal cells from an elderly patient
2015 · Matthias Megges, Sven Geissler, et al. · Stem Cell Research · 8
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Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks
2015 · Amir M Hossini, Matthias Megges, et al. · BMC Genomics · 136
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Mitochondrial Function in Pluripotent Stem Cells and Cellular Reprogramming
2013 · Raul Bukowiecki, James Adjaye, et al. · Gerontology · 82
HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2
2013 · Alessandro Prigione, Nadine Rohwer, et al. · Stem Cells · 255
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BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells
2013 · Björn Lichtner, Petra Knaus, et al. · Biomaterials · 52
Identification of Biomarkers of Human Skin Ageing in Both Genders. Wnt Signalling - A Label of Skin Ageing?
2012 · Evgenia Makrantonaki, Thore C. Brink, et al. · PLoS ONE · 93
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Comparative molecular portraits of human unfertilized oocytes and primordial germ cells at 10 weeks of gestation
2012 · Ferdinand Diedrichs, Barbara Mlody, et al. · The International Journal of Developmental Biology · 10
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