Award

Identify and Develop Mouse Models for Otitis Media

Funder: National Institute on Deafness and Other Communication Disorders

Funding type: research

Funder scheme: R21

Start date: 2003-07-01

End date: 2007-06-30

Investigator: QING Y ZHENG

Institution: CASE WESTERN RESERVE UNIVERSITY

Funded outputs count: 53

Funder award ID: R21DC005846

OpenAlex ID: G6475970159

gom1 Mutant Mice as a Model of Otitis Media

2022 · Tihua Zheng, Wenyi Huang, et al. · Journal of the Association for Research in Otolaryngology · 5

Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media

2022 · Daoli Xie, Tong Zhao, et al. · Frontiers in Cellular Neuroscience · 14

Hearing Loss in Id1−/−; Id3+/− and Id1+/−; Id3−/− Mice Is Associated With a High Incidence of Middle Ear Infection (Otitis Media)

2021 · Qingyin Zheng, Tihua Zheng, et al. · Frontiers in Genetics · 3

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Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene

2021 · Tong Zhao, Peng Ma, et al. · Journal of Neuroscience Research · 8

Autophagy impairment as a key feature for acetaminophen-induced ototoxicity

2021 · Tong Zhao, Tihua Zheng, et al. · Cell Death and Disease · 25

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2020 · Qing Yin Zheng, Lihong Kui, et al. · Neural Plasticity · 9

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Role of Endoplasmic Reticulum Stress in Otitis Media

2020 · Hongchun Zhao, Yanfei Wang, et al. · Frontiers in Genetics · 8

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Current Understanding of Host Genetics of Otitis Media

2020 · Ruishuang Geng, Qingzhu Wang, et al. · Frontiers in Genetics · 23

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Panel 3: Genetics and Precision Medicine of Otitis Media

2017 · Jizhen Lin, Hena Hafrén, et al. · Otolaryngology · 7

Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23 mice

2015 · J. Hu, M. Xu, et al. · Neuroscience · 25

Otitis media induced by peptidoglycan-polysaccharide (PGPS) in TLR2-deficient (Tlr2−/−) mice for developing drug therapy

2015 · Xiaolin Zhang, Tihua Zheng, et al. · Infection Genetics and Evolution · 18

Blocking macrophage migration inhibitory factor activity alleviates mouse acute otitis media in vivo

2014 · Jin Zhang, Min Xu, et al. · Immunology Letters · 20

Alveolar epithelial cells undergo epithelial-mesenchymal transition in acute interstitial pneumonia: a case report

2014 · Hongbo Li, Jinjin Zhang, et al. · BMC Pulmonary Medicine · 8

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Risk Factors for Chronic and Recurrent Otitis Media–A Meta-Analysis

2014 · Yan Zhang, Min Xu, et al. · PLoS ONE · 179

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A New Mutation of the Atoh1 Gene in Mice with Normal Life Span Allows Analysis of Inner Ear and Cerebellar Phenotype in Aging

2013 · Kianoush Sheykholeslami, Vikrum Thimmappa, et al. · PLoS ONE · 13

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Computational fluid dynamics analysis of salivary flow and its effect on sialolithogenesis

2013 · P Zhu, Y Lin, et al. · Oral Diseases · 5

Mutation in Phex Gene Predisposes BALB/c-PhexHyp-Duk/Y Mice to Otitis Media

2012 · Fengchan Han, Heping Yu, et al. · PLoS ONE · 12

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Pathological Features in the Lmna Mutant Mouse Provide a Novel Model of Human Otitis Media and Laminopathies

2012 · Yan Zhang, Heping Yu, et al. · American Journal Of Pathology · 24

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Otitis Media in a New Mouse Model for CHARGE Syndrome with a Deletion in the Chd7 Gene

2012 · Cong Tian, Heping Yu, et al. · PLoS ONE · 29

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Hypoxia-Inducible Factor and Vascular Endothelial Growth Factor Pathway for the Study of Hypoxia in a New Model of Otitis Media with Effusion

2012 · Qiuhong Huang, Zhigang Zhang, et al. · Audiology and Neurotology · 21

Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse

2010 · Cong Tian, Xue Z. Liu, et al. · Brain Research · 30

Otitis media in a mouse model for Down syndrome

2009 · Fengchan Han, Heping Yu, et al. · International Journal of Experimental Pathology · 32

The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development

2009 · Mao Mao, Daniel R. Thedens, et al. · Mammalian Genome · 52

Vestibular Evoked Myogenic Potentials in Normal Mice and Phex Mice With Spontaneous Endolymphatic Hydrops

2009 · Kianoush Sheykholeslami, Cliff A. Megerian, et al. · Otology & Neurotology · 29

Role for Toll-Like Receptor 2 in the Immune Response toStreptococcus pneumoniaeInfection in Mouse Otitis Media

2009 · Fengchan Han, Heping Yu, et al. · Infection and Immunity · 41