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U24DK59635

Funded outputs count: 87
Funder award ID: U24DK59635
OpenAlex ID: G2265312807
Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents
2016 · Rachel J. Perry, Rebecca L. Cardone, et al. · American Journal of Physiology-Endocrinology and Metabolism · 68
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome
2016 · Rachel J. Perry, Liang Peng, et al. · Nature · 1,297
Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids
2015 · Daniel F. Vatner, Sachin K. Majumdar, et al. · Proceedings of the National Academy of Sciences · 235
Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II
2014 · Colleen N. Feriod, Lily Nguyen, et al. · American Journal of Physiology-Endocrinology and Metabolism · 19
Loss of the Endothelial Glucocorticoid Receptor Prevents the Therapeutic Protection Afforded by Dexamethasone after LPS
2014 · Julie E. Goodwin, Yan Feng, et al. · PLoS ONE · 19
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Endothelial glucocorticoid receptor is required for protection against sepsis
2012 · Julie E. Goodwin, Yan Feng, et al. · Proceedings of the National Academy of Sciences · 142
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Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α–dependent function
2012 · Yan Huang, Li Lei, et al. · Proceedings of the National Academy of Sciences · 110
Insulin resistance is associated with elevated serum pigment epithelium–derived factor (PEDF) levels in morbidly obese patients
2012 · Arijeet K. Gattu, Andreas L. Birkenfeld, et al. · Acta Diabetologica · 31
Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2
2011 · P. R. Patel, S. K. Ramakrishnan, et al. · Diabetologia · 19
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Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb’s cycle flux independent of ATP synthesis
2011 · Gary W. Cline, Rebecca L. Pongratz, et al. · Biochemical and Biophysical Research Communications · 19
Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice
2011 · Andreas L. Birkenfeld, Hui-Young Lee, et al. · Cell Metabolism · 215
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Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension
2011 · Julie E Goodwin, Junhui Zhang, et al. · Journal of Hypertension · 52
Lysophosphatidic Acid Activates Peroxisome Proliferator Activated Receptor-γ in CHO Cells That Over-Express Glycerol 3-Phosphate Acyltransferase-1
2011 · Cliona M. Stapleton, Douglas G. Mashek, et al. · PLoS ONE · 52
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Telomere dysfunction induces metabolic and mitochondrial compromise
2011 · Ergün Sahin, Simona Colla, et al. · Nature · 1,319
Inflammatory Induction of Human Resistin Causes Insulin Resistance in Endotoxemic Mice
2011 · Hyeong-Kyu Park, Mohammed Qatanani, et al. · Diabetes · 62
Sirtuin-1 regulation of mammalian metabolism
2010 · Matthew P. Gillum, Derek M. Erion, et al. · Trends in Molecular Medicine · 108
Liver‐Specific Pyruvate Dehydrogenase Complex Deficiency Upregulates Lipogenesis in Adipose Tissue and Improves Peripheral Insulin Sensitivity
2010 · Cheol Soo Choi, Pushpankur Ghoshal, et al. · Lipids · 24
Loss of Par-1a/MARK3/C-TAK1 Kinase Leads to Reduced Adiposity, Resistance to Hepatic Steatosis, and Defective Gluconeogenesis
2010 · Jochen K. Lennerz, Jonathan B. Hurov, et al. · Molecular and Cellular Biology · 55
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Lipid-induced insulin resistance: unravelling the mechanism
2010 · Varman T Samuel, Kitt Falk Petersen, et al. · The Lancet · 1,185
Resistance to High-Fat Diet-Induced Obesity and Insulin Resistance in Mice with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
2010 · Dongyan Zhang, Jennifer Christianson, et al. · Cell Metabolism · 84
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Acyl-coenzyme A synthetases in metabolic control
2010 · Jessica M Ellis, Jennifer L Frahm, et al. · Current Opinion in Lipidology · 227
Glycerol-3-Phosphate Acyltransferase 1 Deficiency in ob/ob Mice Diminishes Hepatic Steatosis but Does Not Protect Against Insulin Resistance or Obesity
2010 · Angela A. Wendel, Lei O. Li, et al. · Diabetes · 63
The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension
2010 · Julie E. Goodwin, Junhui Zhang, et al. · Biochemical and Biophysical Research Communications · 29
PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis
2009 · Jennifer L. Estall, Jorge L. Ruas, et al. · Proceedings of the National Academy of Sciences · 134
Liver-specific Loss of Long Chain Acyl-CoA Synthetase-1 Decreases Triacylglycerol Synthesis and β-Oxidation and Alters Phospholipid Fatty Acid Composition
2009 · Lei O. Li, Jessica M. Ellis, et al. · Journal of Biological Chemistry · 241
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