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AG-09909

Funded outputs count: 51
Funder award ID: AG-09909
OpenAlex ID: G2314803419
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
2015 · Remi-Martin Laberge, Yu Sun, et al. · Nature Cell Biology · 1,160
Mitochondrial DNA damage induces apoptosis in senescent cells
2013 · R-M Laberge, D Adler, et al. · Cell Death and Disease · 82
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p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
2013 · Albert R. Davalos, Misako Kawahara, et al. · The Journal of Cell Biology · 439
Responses of human embryonic stem cells and their differentiated progeny to ionizing radiation
2012 · Ying Zou, Ningzhe Zhang, et al. · Biochemical and Biophysical Research Communications · 41
Lamin B1 loss is a senescence-associated biomarker
2012 · Adam Freund, Remi-Martin Laberge, et al. · Molecular Biology of the Cell · 1,045
Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
2012 · Remi‐Martin Laberge, Lili Zhou, et al. · Aging Cell · 229
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
2011 · Jean-Philippe Coppé, Francis Rodier, et al. · Journal of Biological Chemistry · 506
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p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype
2011 · Adam Freund, Christopher K Patil, et al. · The EMBO Journal · 1,041
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
2010 · Francis Rodier, Denise P. Muñoz, et al. · Journal of Cell Science · 535
p16INK4a‐mediated suppression of telomerase in normal and malignant human breast cells
2010 · Alexey V. Bazarov, Marjolein Van Sluis, et al. · Aging Cell · 25
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Inflammatory networks during cellular senescence: causes and consequences
2010 · Adam Freund, Arturo V. Orjalo, et al. · Trends in Molecular Medicine · 1,354
Senescent cells as a source of inflammatory factors for tumor progression
2010 · Albert R. Davalos, Jean-Philippe Coppe, et al. · Cancer and Metastasis Reviews · 636
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Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
2010 · Oanh N. L. Le, Francis Rodier, et al. · Aging Cell · 167
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
2010 · Jean-Philippe Coppé, Christopher K. Patil, et al. · PLoS ONE · 455
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Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo
2009 · Florence Debacq-Chainiaux, Jorge D Erusalimsky, et al. · Nature Protocols · 1,668
A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrix
2009 · Patrick G. Kaminker, Sahn-Ho Kim, et al. · Cell Cycle · 47
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Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
2009 · Coppé, Jean-Philippe; Patil, Christopher; Rodier, Francis; Sun, Yu; Munoz, Denise; Goldstein, Joshua; Nelson, Peter; Desprez, Pierre-Yves; Campisi, Judith · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · 4,183
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
2008 · Jean-Philippe Coppé, Christopher K Patil, et al. · PLoS Biology · 302
A Role for Fibroblasts in Mediating the Effects of Tobacco-Induced Epithelial Cell Growth and Invasion
2008 · Jean-Philippe Coppe, Megan Boysen, et al. · Molecular Cancer Research · 76
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p53-dependent integration of telomere and growth factor deprivation signals
2007 · Alain Beliveau, Ekaterina Bassett, et al. · Proceedings of the National Academy of Sciences · 38
Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence
2006 · Jean-Philippe Coppé, Katalin Kauser, et al. · Journal of Biological Chemistry · 603
Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2
2005 · Patrick Kaminker, Cedric Plachot, et al. · Journal of Cell Science
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
2005 · Simona Parrinello, Jean-Philippe Coppe, et al. · Journal of Cell Science · 631
TIN2 Mediates Functions of TRF2 at Human Telomeres
2004 · Sahn-ho Kim, Christian Beausejour, et al. · Journal of Biological Chemistry · 214
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Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
2004 · Miguel A Rubio, Albert R Davalos, et al. · Experimental Cell Research · 107
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