Award

2021YFA1101401

Funder: National Key Research and Development Program of China

Funded outputs count: 16

Funder award ID: 2021YFA1101401

OpenAlex ID: G2317025226

Histone modifications and chromatin landscapes in microglial function: Developmental imprinting and disease-associated reprogramming

2026 · Xiao Li, Rong-Liang Guo, et al. · Ageing Research Reviews

Amyloid-β suppresses oligodendrocyte differentiation in adult oligodendrocyte precursor cells (OPCs), with inflammatory gene changes distinguishing it from developmental OPCs

2026 · Daopeng Li, Wenxiu Dai, et al. · Journal of Alzheimer s Disease

Systematic profiling reveals betaine as an exercise mimetic for geroprotection

2025 · Lingling Geng, Jiale Ping, et al. · Cell · 32

A single-cell transcriptomic atlas reveals senescence and inflammation in the post-tuberculosis human lung

2025 · Guoqiang Sun, Kuan Li, et al. · Nature Microbiology · 15

ZBP1 senses splicing aberration through Z-RNA to promote cell death

2025 · Zhang-Hua Yang, Puqi Wu, et al. · Molecular Cell · 26

Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging

2024 · Shuai Ma, Zhejun Ji, et al. · Cell · 162

The Role of Protein Quantity Control in Polyglutamine Spinocerebellar Ataxias

2024 · Hongfeng Zhang, Xin Wang · The Cerebellum · 4

Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity

2024 · Na Wang, Lujian Cai, et al. · iScience · 16

Alzheimer’s disease: insights into pathology, molecular mechanisms, and therapy

2024 · Qiuyang Zheng, Xin Wang · Protein & Cell · 432

A ZBP1 isoform blocks ZBP1-mediated cell death

2024 · Zhi-Yu Cai, Puqi Wu, et al. · Cell Reports · 20

P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy

2024 · Denghong Zhang, Wei Zhang, et al. · Neuron · 73

A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes

2023 · Shanshan Yang, Chengyu Liu, et al. · Protein & Cell · 63

Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner

2023 · Jinghui Lei, Xiaoyu Jiang, et al. · Protein & Cell · 14

β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function

2023 · Yue Gao, Yujuan Hong, et al. · Cell · 75

Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration

2022 · Qian Zhao, Yandong Zheng, et al. · Protein & Cell · 34

A comparative study of metformin and nicotinamide riboside in alleviating tissue aging in rats

2022 · Lingling Geng, Bin Zhang, et al. · Life Medicine · 37