Environmental Epigenomics and Precision Environmental Health
Description: Project Narrative It is increasingly recognized that exposures to toxicants affect health and disease by not only mutating genes, but also by modifying the epigenome, alterations to DNA that are heritable and lead to disease when deregulated. Our research will advance the understanding of the effects of perinatal exposures (e.g. metals such as lead and endocrine disrupting chemicals such as phthalates) on the epigenome and health risks as well as develop new tools, based on the PIWI-interacting RNA (piRNA) system to transform precision environmental health.
Funding type: research
Funder scheme: R35
Start date: 2020-05-11
End date: 2028-03-31
Investigator: DANA DOLINOY
Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
Funded outputs count: 77
Funder award ID: R35ES031686
OpenAlex ID: G9000862967