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Delivery of Sleeping Beauty Transposons to Dog Liver for Gene Therapy

Funding type: research
Funder scheme: R41
Start date: 2008-08-15
End date: 2011-01-31
Investigator: PERRY B. HACKETT
Institution: DISCOVERY GENOMICS, INC.
Funded outputs count: 4
Funder award ID: R41DK081249
OpenAlex ID: G1082874237
Prolonged Expression of Secreted Enzymes in Dogs After Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease
2017 · Elena L. Aronovich, Kendra A. Hyland, et al. · Human Gene Therapy · 10
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Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy
2013 · Perry B. Hackett, David A. Largaespada, et al. · Translational research · 96
Targeting DNA With Fingers and TALENs
2012 · Daniel F Carlson, Scott C Fahrenkrug, et al. · Molecular Therapy — Nucleic Acids · 133
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DDE transposases: Structural similarity and diversity
2010 · Irina V. Nesmelova, Perry B. Hackett · Advanced Drug Delivery Reviews · 90
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