Award

U19 CA148065

Funded outputs count: 130

Funder award ID: U19 CA148065

OpenAlex ID: G2395980551

Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer

2026 · Billaud, Amandine, Figlioli, Gisella, et al. · Apollo (University of Cambridge)

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups

2026 · Hagai Levi, Qin Wang, et al. · medRxiv

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Comparative fine-mapping of breast cancer susceptibility loci using summary statistics methods and multinomial regression

2026 · Denise G. O’Mahony, Jonathan Beesley, et al. · medRxiv

Natural menopause, menarche and breast cancer risk in BRCA1 and BRCA2 pathogenic variant carriers: a Mendelian randomization analysis

2026 · Nasim Mavaddat, Daniel R. Barnes, et al. · British Journal of Cancer

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A reanalysis of a genome-wide association study on breast cancer in Asian populations using the SG10K_Health reference panel for imputation: a multi-Centre case–control analysis

2026 · Xuling Chang, Shivaani Mariapun, et al. · Human Molecular Genetics

Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

2025 · Daniel R. Barnes, Jonathan P. Tyrer, et al. · npj Genomic Medicine · 1

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Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

2025 · Barnes, Daniel R, Tyrer, Jonathan P, et al. · eScholarship (California Digital Library)

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Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer

2025 · Amandine Billaud, Gisella Figlioli, et al. · The Breast · 2

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Causal plasma metabolites for breast cancer risk: a two-sample Mendelian randomization study with colocalization evidence

2025 · Hanghang Chen, Yueyuan Xu, et al. · Discover Oncology

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Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis

2025 · Emma Hazelwood, Lucy J Goudswaard, et al. · JNCI Journal of the National Cancer Institute · 4

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Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification

2025 · Maria Zanti, Denise G. O’Mahony, et al. · Nature Communications · 11

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Interactions between genetic and epidemiological factors influencing mammographic density

2025 · Austin Hammermeister Suger, Hongjie Chen, et al. · American Journal of Epidemiology

Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries

2025 · Peh Joo Ho, Christine Kim Yan Loo, et al. · medRxiv

The impact of sleep on breast cancer-specific mortality: a Mendelian randomisation study

2025 · Bryony L. Hayes, Leanne Fleming, et al. · BMC Cancer · 3

Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer

2025 · Reiner Hoppe, Stefan Winter, et al. · npj Breast Cancer · 1

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Polygenic risk scores stratify breast cancer risk among women with benign breast disease

2024 · Mark E Sherman, Stacey J Winham, et al. · JNCI Journal of the National Cancer Institute · 7

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Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers

2024 · Joon Ho Kang, Youngkee Lee, et al. · Communications Biology · 9

Characterizing the Relationship between Expression Quantitative Trait Loci (eQTLs), DNA Methylation Quantitative Trait Loci (mQTLs), and Breast Cancer Risk Variants

2024 · Peh Joo Ho, Alexis Khng, et al. · Cancers · 4

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A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer

2024 · Guimin Gao, Julian McClellan, et al. · The American Journal of Human Genetics · 12

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions

2024 · Stacey E.P. Joosten, Sebastian Gregoricchio, et al. · Genome Research · 5

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Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

2024 · Figueroa, J., Lee, D.G., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

2024 · Clarke, C.L., Anton-Culver, H., et al. · Kölner Universitäts PublikationsServer (Universität zu Köln)

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Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

2024 · Castelao, J.E., Geisler, J., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)

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Combined Associations of a Polygenic Risk Score and Classical Risk Factors with Breast Cancer Risk

2024 · Mavaddat, N., Schoemaker, M.J., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)

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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

2024 · Koutros, S., Janni, W., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)

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