IgG and Adipose Pathological Remodeling
Description: PROJECT NARRATIVE This project addresses a significant unmet medical need for curbing metabolic dysfunctions in obesity by investigating a novel mechanism underlying adipose tissue pathological remodeling. The proposed studies will establish the role of Immunoglobulin G (IgG) in adipose tissue dysfunction and further elucidate the regulatory and functioning mechanisms. This project will provide a novel therapeutic strategy by targeting IgG recycling to treat obesity and comorbidities.
Funding type: research
Funder scheme: R01
Start date: 2023-03-06
End date: 2027-02-28
Investigator: ANTHONY W FERRANTE
Institution: COLUMBIA UNIVERSITY HEALTH SCIENCES
Funded outputs count: 4
Funder award ID: R01DK134471
OpenAlex ID: G9000875805