Award

AG 16768

Funded outputs count: 45

Funder award ID: AG 16768

OpenAlex ID: G2513486073

Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in HereditaryGNEInclusion-Body Myopathy

2015 · Anna Nogalska, Carla D’Agostino, et al. · Journal of Neuropathology & Experimental Neurology · 20

Sporadic inclusion-body myositis: A degenerative muscle disease associated with aging, impaired muscle protein homeostasis and abnormal mitophagy

2014 · Valerie Askanas, W. King Engel, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 107

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Pathogenic Considerations in Sporadic Inclusion-Body Myositis, a Degenerative Muscle Disease Associated With Aging and Abnormalities of Myoproteostasis

2012 · Valerie Askanas, W. King Engel, et al. · Journal of Neuropathology & Experimental Neurology · 72

Activation of the γ-secretase complex and presence of γ-secretase-activating protein may contribute to Aβ42 production in sporadic inclusion-body myositis muscle fibers

2012 · Anna Nogalska, Carla D'Agostino, et al. · Neurobiology of Disease · 14

Novel demonstration of amyloid-β oligomers in sporadic inclusion-body myositis muscle fibers

2010 · Anna Nogalska, Carla D’Agostino, et al. · Acta Neuropathologica · 42

In sporadic inclusion body myositis muscle fibres TDP-43-positive inclusions are less frequent and robust than p62 inclusions, and are not associated with paired helical filaments

2010 · C. D'Agostino, A. Nogalska, et al. · Neuropathology and Applied Neurobiology · 33

Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers

2010 · Anna Nogalska, Carla D'Agostino, et al. · American Journal Of Pathology · 114

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Increased BACE1 mRNA and noncoding BACE1-antisense transcript in sporadic inclusion-body myositis muscle fibers—Possibly caused by endoplasmic reticulum stress

2010 · Anna Nogalska, W. King Engel, et al. · Neuroscience Letters · 34

In AβPP‐overexpressing cultured human muscle fibers proteasome inhibition enhances phosphorylation of AβPP751 and GSK3β activation: effects mitigated by lithium and apparently relevant to sporadic inclusion‐body myositis

2009 · Chiara Terracciano, Anna Nogalska, et al. · Journal of Neurochemistry · 38

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis

2009 · Anna Nogalska, Chiara Terracciano, et al. · Acta Neuropathologica · 144

Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra‐Muscle Fiber Multi‐Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation

2009 · Valerie Askanas, W. King Engel, et al. · Brain Pathology · 140

Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer’s and Parkinson’s disease brains

2008 · Valerie Askanas, W. King Engel · Acta Neuropathologica · 123

Decreased SIRT1 deacetylase activity in sporadic inclusion-body myositis muscle fibers

2008 · Anna Nogalska, Carla D’Agostino, et al. · Neurobiology of Aging · 22

In inclusion-body myositis muscle fibers Parkinson-associated DJ-1 is increased and oxidized

2008 · Chiara Terracciano, Anna Nogalska, et al. · Free Radical Biology and Medicine · 30

Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis

2007 · Valerie Askanas, W King Engel · Current Opinion in Rheumatology · 98

NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in AβPP-overexpressing cultured human muscle fibers

2007 · Slawomir Wojcik, W. King Engel, et al. · Acta Neuropathologica · 38

Myostatin precursor protein is increased and associates with amyloid‐β precursor protein in inclusion‐body myositis culture model

2007 · S. Wojcik, A. Nogalska, et al. · Neuropathology and Applied Neurobiology · 17

Endoplasmic reticulum stress induces myostatin precursor protein and NF-κB in cultured human muscle fibers: Relevance to inclusion body myositis

2006 · Anna Nogalska, Slawomir Wojcik, et al. · Experimental Neurology · 54

AβPP-overexpression and proteasome inhibition increase αB-crystallin in cultured human muscle: Relevance to inclusion-body myositis

2006 · Slawomir Wojcik, W. King Engel, et al. · Neuromuscular Disorders · 31

Homocysteine‐induced endoplasmic reticulum protein (Herp) is up‐regulated in sporadic inclusion‐body myositis and in endoplasmic reticulum stress‐induced cultured human muscle fibers

2006 · Anna Nogalska, W. King Engel, et al. · Journal of Neurochemistry · 63

Inclusion-body myositis

2006 · Valerie Askanas, W. King Engel · Neurology · 168

Inclusion-body myositis

2006 · W. King Engel, Valerie Askanas · Neurology · 142

Proteasome Inhibition and Aggresome Formation in Sporadic Inclusion-Body Myositis and in Amyloid-β Precursor Protein-Overexpressing Cultured Human Muscle Fibers

2005 · Pietro Fratta, W. King Engel, et al. · American Journal Of Pathology · 111

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Molecular pathology and pathogenesis of inclusion‐body myositis

2005 · Valerie Askanas, W. King Engel · Microscopy Research and Technique · 50

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Myostatin is increased and complexes with amyloid-β within sporadic inclusion-body myositis muscle fibers

2005 · Sławomir Wójcik, W. King Engel, et al. · Acta Neuropathologica · 39