Regulatory mechanisms of senescence-derived secretory phenotype (SASP) in oral cancer progression in aging mice
Description: Senescence-associated secretory phenotype (SASP) is implicated in various age-related diseases. In aging mice, to delineate the regulatory mechanisms of SASP-driven oral cancer we will use the Cre/loxP system and photo-isolation chemistry techniques to detect senescent cells and their SASP profile.
Amount: ¥4,810,000
Funding type: fellowship
Funder scheme: Grant-in-Aid for Early-Career Scientists
Start date: 2025-04-01
End date: 2028-03-31
Investigator: Desai Karishma
Institution: Tokyo Dental College
Funded outputs count: 2
Funder award ID: 25K20385
OpenAlex ID: G252340737