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S10-OD030286
Funder:
NIH Office of the Director
Funded outputs count:
50
Funder award ID:
S10-OD030286
OpenAlex ID:
G2533196969
NAD Metabolism Drives CTCF-Cohesin Chromatin Regulation in EBV-Transformed B-Cells
2026
·
Davide Maestri
, Rachel Sklutuis
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
PRMT5 activity sustains histone production to maintain genome integrity
2026
·
Jacob S. Roth
, Joseph D. DeAngelo
, et al.
·
Nature Communications
·
6
PDF
Cross-linking mass spectrometry guided structure prediction of disordered Encephalitozoon hellem proteins
2026
·
Elizabeth Weyer
, Yongliang Wang
, et al.
·
mBio
Developmental rewiring of EHMT1 function during human cortical neurogenesis
2026
·
Kritika Kasliwal
, Kaushiki Chatterjee
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells
2026
·
Rebecca Sereda
, Kristen Lindenau
, et al.
·
Nature Aging
·
4
PDF
Exploiting an epigenetic resistance mechanism to PI3-kinase inhibition in leukemic stem cells
2026
·
Shira G. Glushakow-Smith
, Imit Kaur
, et al.
·
Leukemia
PDF
Acetyl-CoA–dependent processes are preferentially supported by local metabolite synthesis
2026
·
Julianna G. Supplee
, Pedro Costa-Pinheiro
, et al.
·
Science Advances
Ribosomal proteins are major substrates of starvation-induced endosomal microautophagy in Drosophila
2026
·
Prasoon Jaya
, Satya Surabhi
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
A KDM5 variant outside the catalytic Jumonji C domain disrupts demethylase activity and alters the proximity interactome
2026
·
Melissa A Castiglione
, Matanel Yheskel
, et al.
·
G3 Genes Genomes Genetics
·
1
PDF
Regulatory T cell immunosuppressive function requires chaperone-mediated autophagy
2026
·
Ranee Harrison
, Floralba Gjergjova
, et al.
·
Autophagy
·
1
ATF4 coordinates amino acid and nucleotide synthesis with selective protein translation to ensure proper DNA replication timing in leukemia cells
2026
·
Jacklyn M. Huhn
, Liana Valin
, et al.
·
Nature Communications
·
2
PDF
Single-molecule imaging reveals RNA polymerase II dynamics and TAF1-dependent promoter-proximal pause release
2026
·
Nayem Haque
, Ronald Cutler
, et al.
·
Nature Communications
·
1
Histone succinylation directly inhibits Jumonji domain demethylases and stabilizes repressive chromatin states
2026
·
Sarah Graff
, Stephanie Stransky
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Chaperone-mediated autophagy is required for regulatory T cell function
2026
·
Ranee Harrison
, Floralba Gjergjova
, et al.
·
Nature Communications
·
3
PDF
Methionine Restriction Extends Yeast Lifespan by Activating Non‐Nitrogen‐Starvation‐Induced Autophagy Through Limiting Methylation of Protein Phosphatase 2A
2026
·
Kaylah Birmingham
, Nina Arslanovic
, et al.
·
Aging Cell
·
1
Glucose-dependent spatial and temporal modulation of oligodendrocyte progenitor cell proliferation via ACLY-regulated histone acetylation
2026
·
Sami Sauma
, Stephanie Stransky
, et al.
·
Nature Neuroscience
·
4
HIV-1 infection induces Vif-mediated SUMOylation of host RNA splicing factors important for proper viral RNA splicing
2026
·
Demetra P. Kelenis
, Jeffrey R. Johnson
, et al.
·
Proceedings of the National Academy of Sciences
·
3
PDF
Single-Cell RNA Analysis of Murine Osteosarcoma Uncovers Skp2 Function in Metastasis, Genomic Instability, and Immune Activation and Reveals Additional Target Pathways
2026
·
Alexander Ferrena
, Ranxin Zhang
, et al.
·
Cancer Research Communications
·
2
Disruption of CSF-1 receptor–mediated metal ion homeostasis in the murine brain promotes neurodegenerative disease
2026
·
Violeta Chițu
, Julia Alvarenga
, et al.
·
Journal of Clinical Investigation
·
1
PDF
Extracellular vesicles of Emergomyces africanus modulate host immune responses and reflect metabolic adaptations to nutrient availability
2026
·
Leandro Honorato
, Albaniza Liuane Ribeiro do Nascimento Sabino
, et al.
·
Infection and Immunity
·
1
Adaptor-mediated recruitment of three dyneins to dynactin enhances force generation
2026
·
Lu Rao
, Xinglei Liu
, et al.
·
Nature Cell Biology
·
14
PDF
Impact of Tau overexpression on DNA replication dynamics in centromeres of human neural progenitor cells
2026
·
Elisa Balzano
, Shyam Twayana
, et al.
·
iScience
Direct Injection Mass Spectrometry and iFishMass for the High-Throughput Analysis of Antibody Modifications
2025
·
Jennifer Aguilan
, Carlos Madrid-Aliste
, et al.
·
ACS Pharmacology & Translational Science
·
2
Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity
2025
·
Stephanie Stransky
, Sarah Graff
, et al.
·
Aging Cell
·
7
PDF
Reduced IGF-1 signaling fails to limit Alzheimer’s disease progression in a novel rat model of IGF-1R haploinsufficiency
2025
·
Sushma Narayan
, Kai Mao
, et al.
·
Scientific Reports
·
3
PDF
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