Psychiatric Genomics Consortium for PTSD
Description: Project Narrative Up to 50% of the variance determining who develops Posttraumatic Stress Disorder following a severe trauma may be genetic; however, most successful analyses to date suggest that risk arises from multiple common genetic variants of small effect size, and that very large sample sizes will be needed for detection. This proposal aims to uncover the genomic architecture of PTSD through large-scale, collaborative genome- wide association studies. Identifying the pathways underlying PTSD will lead to an improved neurobiological understanding, enhanced prevention, and improved treatment of this debilitating and prevalent syndrome.
Funding type: research
Funder scheme: R01
Start date: 2016-08-19
End date: 2029-03-31
Investigator: KARESTAN C KOENEN
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Funded outputs count: 110
Funder award ID: R01MH106595
OpenAlex ID: G9000881762