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Antecedents of Adult Physical Health and Cognitive Risks for Alzheimer's Disease and Related Dementias (ADRD) in Adolescent Family Experiences: A Prospective, Longitudinal Adoption Study

Description: NARRATIVE Children who receive less warmth, support, and responsiveness from their parents typically have higher inflammation levels, blood pressure, and allostatic load, indicators that predict future cardiovascular problems, reduced cognitive functioning, and risk for Alzheimer’s Disease and Related Dementias (ADRD). This project examines the significance of family experiences in adolescence for physical and cognitive health outcomes in adulthood by conducting a follow-up into midlife of the Sibling Interaction and Behavior Study (SIBS), a longitudinal study of 409 adoptive and 208 non-adoptive families. The adoption design of the study allows a strong test of the hypothesis that family experiences are linked to physical health and cognitive outcomes with downstream implications for Alzheimer’s Disease and Related Dementias (ADRD) risk through environmental pathways.
Funding type: research
Funder scheme: R01
Start date: 2022-06-01
End date: 2027-03-31
Investigator: ROBERT F KRUEGER
Institution: UNIVERSITY OF MINNESOTA
Funded outputs count: 22
Funder award ID: R01AG077742
OpenAlex ID: G9000875433
2026 · Alisha A. Crump, Jemar R. Bather, et al. · Brain Behavior & Immunity - Health
2025 · Isaac T. Petersen, Zachary Demko, et al. · Psychological Assessment · 2
2025 · Colin D Freilich, Robert F Krueger · Current Opinion in Behavioral Sciences
2025 · Robel Alemu, Anastasia Terskaya, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
2025 · Patrick D. McGorry, Ian B. Hickie, et al. · Psychological Medicine · 42
2024 · Zachary S. Michal, Craig A. Marquardt, et al. · Psychological Medicine · 4
2024 · Samuel E. Cooper, Emily R. Perkins, et al. · Journal of Psychopathology and Clinical Science · 12
2024 · Colin D Freilich, Kristian E Markon, et al. · The Journals of Gerontology Series B · 19
2024 · Darren Haywood, Roman Kotov, et al. · Trends in cancer · 21
2024 · Colin D. Freilich, Kristian E. Markon, et al. · Psychology and Aging · 28
2023 · Colin D. Freilich, Isabella M. Palumbo, et al. · Psychological Assessment · 8
2023 · Zlatan Krizan, Colin Freilich, et al. · Journal of Sleep Research · 7
2022 · Ashley L. Watts, Robert D. Latzman, et al. · Psychology of Addictive Behaviors · 25
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