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C62187/A29760
Funder:
Cancer Research UK
Funded outputs count:
23
Funder award ID:
C62187/A29760
OpenAlex ID:
G2706141419
Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platform
2026
·
Hui-Ling Ou
, Reuben Hoffmann
, et al.
·
Cell Death and Disease
PDF
Urinary detection of therapy-induced senescence and fibrosis using an injectable albumin-based nanoprobe
2026
·
Muhamad Hartono
, Jianfeng Ge
, et al.
·
Nature Aging
·
2
PDF
Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFβ senescent secretome
2026
·
Estela González-Gualda
, Marika A. V. Reinius
, et al.
·
Nature Aging
·
18
Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
2025
·
Jianfeng Ge
, Shoko Hirosue
, et al.
·
EMBO Molecular Medicine
·
3
PDF
Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
2025
·
Jianfeng Ge
, Shoko Hirosue
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Improved Therapeutic Efficiency of Senescent Cell‐specific, Galactose‐Functionalized Micelle Nanocarriers
2024
·
Badri Parshad
, Andrew George Baker
, et al.
·
Small
·
17
PDF
Inhibition of lung tumorigenesis by transient reprogramming in cancer cells
2024
·
Pablo Pedrosa
, Zhenguang Zhang
, et al.
·
Cell Death and Disease
·
5
PDF
An Indocyanine Green‐Based Nanoprobe for In Vivo Detection of Cellular Senescence
2024
·
Andrew G. Baker
, Muhamad Hartono
, et al.
·
Angewandte Chemie
·
2
PDF
An Indocyanine Green‐Based Nanoprobe for In Vivo Detection of Cellular Senescence
2024
·
Andrew G. Baker
, Muhamad Hartono
, et al.
·
Angewandte Chemie International Edition
·
30
PDF
Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer
2023
·
Pablo Pedrosa
, Zhenguang Zhang
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
2023
·
Scott Haston
, Estela Gonzalez-Gualda
, et al.
·
Cancer Cell
·
251
PDF
Data from Targeting Senescence as a Therapeutic Opportunity for Triple-Negative Breast Cancer
2023
·
Bruno de Paula
, Rosalind Kieran
, et al.
Targeting Senescence as a Therapeutic Opportunity for Triple-Negative Breast Cancer
2023
·
Bruno de Paula
, Rosalind Kieran
, et al.
·
Molecular Cancer Therapeutics
·
30
SARS-CoV-2-induced senescence as a potential therapeutic target
2022
·
Mary Denholm
, Robert C. Rintoul
, et al.
·
European Respiratory Journal
·
4
PDF
Brain Cell Senescence: A New Therapeutic Target for the Acute Treatment of Ischemic Stroke
2022
·
Júlia Baixauli-Martín
, Alicia Aliena-Valero
, et al.
·
Journal of Neuropathology & Experimental Neurology
·
21
Activatable senoprobes and senolytics: Novel strategies to detect and target senescent cells
2022
·
Samir Morsli
, Gary J. Doherty
, et al.
·
Mechanisms of Ageing and Development
·
42
Size-tuneable and immunocompatible polymer nanocarriers for drug delivery in pancreatic cancer
2022
·
Andrea Bistrović Popov
, Francesca Melle
, et al.
·
Nanoscale
·
23
PDF
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea
2021
·
Jose M. Bermúdez-Muñoz
, Adelaida M. Celaya
, et al.
·
Antioxidants
·
18
PDF
Cellular senescence in cancer: from mechanisms to detection
2020
·
Hui‐Ling Ou
, Reuben Hoffmann
, et al.
·
Molecular Oncology
·
193
PDF
A guide to assessing cellular senescence in vitro and in vivo
2020
·
Estela González‐Gualda
, Andrew G. Baker
, et al.
·
FEBS Journal
·
645
Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity
2020
·
Estela González‐Gualda
, Marta Pàez‐Ribes
, et al.
·
Aging Cell
·
303
PDF
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