A Metabolomic Approach to Discovering Biomarkers for ADPKD
Description: NARRATIVE ADPKD is the most prevalent inherited renal disease accounting for 4% of the ESRD population. At present, other than genotyping, which is successful only 85% of the time, there is no test to diagnose the disease in its early, pre-cystic stages at which time novel therapies have the best chance of being effective. This project will lead to a simple, office-based urine and/or blood test for detection of ADPKD, which can be utilized in the primary care, nephrology, and urology clinics and which will lead to earlier treatment of this relatively common disease. In addition, work from this proposal will lead to new knowledge about the pathology of the disease and to selection of patients who will most benefit from any new drug.
Funding type: research
Funder scheme: R01
Start date: 2009-08-17
End date: 2013-06-30
Investigator: ROBERT H. WEISS
Institution: UNIVERSITY OF CALIFORNIA AT DAVIS
Subfield: Genetics
Domain: Life Sciences
Funded outputs count: 44
Funder award ID: R01DK082690
OpenAlex ID: G4199973389