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2021YFA1100300
Funder:
National Key Research and Development Program of China
Funded outputs count:
39
Funder award ID:
2021YFA1100300
OpenAlex ID:
G2733965020
Genomic structural variations distinguishing archaic and modern humans are associated with neurodevelopment
2026
·
Shiyu Zha
, Cheng Li
, et al.
·
iScience
The R-loop-SPT6-SETD2 axis safeguards H3K36me3 to prevent broad H3K4me3 invasion in mouse oocytes
2026
·
Yingliang Sheng
, Tianyan Guo
, et al.
·
Cell Reports
R-loop homeostasis at transposable elements safeguards transcriptional silencing in replication-quiescent oocytes
2026
·
Shao-Yuan Liu
, Xin-Yi Tian
, et al.
·
Nature Communications
Spatiotemporal Transcriptomics Characterizes Immune Microenvironment During Mouse Liver Aging
2026
·
Jiahua Lu
, Yuqian Wang
, et al.
·
Aging Cell
Single-cell analysis reveals essential lncRNAs regulating human trophoblast lineage differentiation
2026
·
Weiyi Zhang
, Chunyan Le
, et al.
·
Life Medicine
An integrated multi-omics and network analysis of neutrophil differentiation from initial- to late-stage
2026
·
Qing Chen
, Tianchang Yang
, et al.
·
Genome biology
CTCF’s loop-independent functions prevail over chromatin looping in the acute degradation system
2025
·
Gongcheng Hu
, Binrui Ji
, et al.
·
Protein & Cell
·
1
Maternal mRNA clearance is associated with the prevention of precocious transcription and genome instability in mouse early embryos
2025
·
Qian-Qian Sha
, Yun-Wen Wu
, et al.
·
中国科学通报:英文版
·
1
GA-binding protein alpha ensures proper blastocyst development by suppressing SMAD3-mediated transforming growth factor-beta signaling
2025
·
Junzhi Liao
, Ying Ma
, et al.
·
Protein & Cell
·
2
Trophectoderm-like cells from EPS cells enable generating EPS cell-derived post-implantation embryoids that complete gastrulation
2025
·
Xuyang Wang
, Ruoqi Cheng
, et al.
·
Protein & Cell
Multi‐omics integration analysis identifies INPP4B as a T‐cell‐specific activation suppressor
2025
·
Ting Peng
, Qing Fang
, et al.
·
Clinical and Translational Medicine
·
1
PDF
Multi-omics analysis reveals single-cell meiotic hotspot dynamics and epigenomic regulations in female mammals
2025
·
Jingyi Li
, Jiansen Lu
, et al.
·
Cell Reports
·
3
Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming
2025
·
Wenxue Zhao
, Weihong Yuan
, et al.
·
Communications Biology
·
16
PDF
Explosive tumor growth in a patient with colon cancer is associated with reduced neoantigen levels and decreased interferon-gamma (IFN-γ) signaling
2025
·
Yaqi Wang
, Jiahua Lu
, et al.
·
BMC Cancer
·
3
PDF
RNA G-quadruplex removal promotes a translational switch after meiosis resumption
2025
·
Qiong-Wen Lu
, Shao-Yuan Liu
, et al.
·
Nucleic Acids Research
·
5
PDF
CTCF Point Mutation at R567 Disrupts Mouse Heart Development via 3D Genome Rearrangement and Transcription Dysregulation
2024
·
Huawei Ren
, Hongxin Zhong
, et al.
·
Cell Proliferation
·
7
PDF
Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development
2024
·
Yuting Liu
, Xin Luo
, et al.
·
Developmental Cell
·
16
BIN2 inhibition suppress ovarian cancer progression meanwhile protect ovarian function through downregulating HDAC1 and RPS6 phosphorylation respectively
2024
·
Cong‐Rong Li
, Shi‐Ya Xie
, et al.
·
Clinical and Translational Medicine
·
1
PDF
Long-Range Enhancer Networks Gradually Emerge as Key Regulators During Human Cortical Neurogenesis
2024
·
Lumeng Jia
, Yingping Hou
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Remodeling ceramide homeostasis promotes functional maturation of human pluripotent stem cell-derived β cells
2024
·
Huijuan Hua
, Yaqi Wang
, et al.
·
Cell stem cell
·
25
Chromatin landscape instructs precise transcription factor regulome during embryonic lineage specification
2024
·
Liping Wang
, Shanru Yi
, et al.
·
Cell Reports
·
10
TEAD2 initiates ground-state pluripotency by mediating chromatin looping
2024
·
Rong Guo
, Xiaotao Dong
, et al.
·
The EMBO Journal
·
3
PDF
Defining a TFAP2C-centered transcription factor network during murine peri-implantation
2024
·
Rui Gao
, Guang Yang
, et al.
·
Developmental Cell
·
21
The effect of trisomic chromosomes on spatial genome organization and global transcription in embryonic stem cells
2024
·
Mengfan Li
, Junsheng Yang
, et al.
·
Cell Proliferation
·
2
ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice
2024
·
Wen Wang
, Rui Gao
, et al.
·
Genes & Development
·
20
PDF
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