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MelBrainSys - Modellbasierte Vorhersage und experimentelle Validierung neuer therapeutischer Interventionen für Melanom-Hirnmetastasen - Charakterisierung der Immunarchitektur und der immunmodulatorischen Fähigkeiten von Melanom-Hirnmetastasen

Amount: €1,223,000
Funding type: grant
Funder scheme: Systemmedizin
Start date: 2019-12-01
End date: 2025-12-31
Institution: Technische Universität Dresden
Funded outputs count: 8
Funder award ID: 01ZX1913C
OpenAlex ID: G2786875979
Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer
2025 · Rebecca Rothe, Antje Tunger, et al. · Frontiers in Immunology · 2
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Tertiary Lymphoid Structures Are Associated with Progression-Free Survival of Peripheral Neuroblastic Tumor Patients
2025 · Rebecca Rothe, Therés Golle, et al. · Cancers · 2
T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels
2024 · Julia M. Messmer, Calvin Thommek, et al. · Immunity · 24
Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients
2024 · Johanna Kirchner, Ioana Plesca, et al. · Frontiers in Immunology · 14
Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
2024 · Susann Winter, Katharina S. Götze, et al. · Leukemia · 41
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BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS ‐mutant melanoma cells: Insights into mode of action and resistance mechanisms
2023 · Lisa Dinter, Paula C. Karitzky, et al. · International Journal of Cancer · 14
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Prognostic impact of the post-treatment T cell composition and spatial organization in soft tissue sarcoma patients treated with neoadjuvant hyperthermic radio(chemo)therapy
2023 · Luise Rupp, Antonia Resag, et al. · Frontiers in Immunology · 11
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Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma
2022 · Ioana Plesca, Iva Benešová, et al. · Cancers · 33
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