Award

S_1731

Funded outputs count: 19

Funder award ID: S_1731

OpenAlex ID: G2788032975

Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis

2024 · Eric W Prince, John R Apps, et al. · Neuro-Oncology · 39

Contemporary Biological Insights and Clinical Management of Craniopharyngioma

2022 · John Richard Apps, Hermann Lothar Muller, et al. · Endocrine Reviews · 85

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A promising future for hypothalamic dysfunction in craniopharyngioma

2022 · John Richard Apps, Juan Pedro Martinez-Barbera · Neuro-Oncology · 4

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CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma

2020 · J. R. Apps, C. Stache, et al. · Neuropathology and Applied Neurobiology · 34

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Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause

2019 · Sara Pozzi, Sarah Bowling, et al. · Stem Cell Reports · 14

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Learning from cases: Analysis of two cases of craniopharyngioma from the 19th to the 21st centuries.

2019 · John R. Apps, J. Ciaran Hutchinson, et al. · F1000Research · 1

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SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma

2019 · G Carreno, J K R Boult, et al. · Endocrine Related Cancer · 41

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Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ

2018 · Paraskevi Xekouki, Emily J Lodge, et al. · Endocrine Related Cancer · 22

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Paracrine roles of cellular senescence in promoting tumourigenesis

2018 · Jose Mario Gonzalez-Meljem, John Richard Apps, et al. · British Journal of Cancer · 183

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Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target

2018 · John R. Apps, Gabriela Carreno, et al. · Acta Neuropathologica · 188

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Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

2017 · Jose Mario Gonzalez-Meljem, Scott Haston, et al. · Nature Communications · 130

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Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours

2017 · Thomas J. Stone, Angus Keeley, et al. · Acta Neuropathologica · 77

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Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors

2017 · Gabriela Carreno, John R. Apps, et al. · Development · 66

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Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma

2017 · Andrew M Donson, John Apps, et al. · Journal of Neuropathology & Experimental Neurology · 114

Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma

2017 · Jessica K. R. Boult, John R. Apps, et al. · Brain Pathology · 18

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Genetically engineered mouse models of craniopharyngioma: an opportunity for therapy development and understanding of tumor biology

2017 · John Richard Apps, Juan Pedro Martinez‐Barbera · Brain Pathology · 21

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MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharyngioma

2017 · S. Haston, S. Pozzi, et al. · Development · 79

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Molecular pathology of adamantinomatous craniopharyngioma: review and opportunities for practice

2016 · John Richard Apps, Juan Pedro Martinez-Barbera · Neurosurgical FOCUS · 49

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Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion

2016 · John R. Apps, J. Ciaran Hutchinson, et al. · Acta Neuropathologica Communications · 50

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