Award

Gene Expression Profiling, Oxidative Stress and Aging

Funder: National Institute on Aging

Funding type: research

Funder scheme: R01

Start date: 2001-03-01

End date: 2007-02-28

Investigator: RICHARD WEINDRUCH

Institution: UNIVERSITY OF WISCONSIN MADISON

Funded outputs count: 26

Funder award ID: R01AG018922

OpenAlex ID: G5233928518

Genes encoding mitochondrial respiratory chain components are profoundly down-regulated with aging in the cochlea of DBA/2J mice

2007 · Shinichi Someya, Tatsuya Yamasoba, et al. · Brain Research · 43

An adaptive alpha spending algorithm improves the power of statistical inference in microarray data analysis

2007 · Jacob P.L. Brand, Lang Chen, et al. · Bioinformation · 2

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The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ

2007 · Shinichi Someya, Tatsuya Yamasoba, et al. · Neurobiology of Aging · 89

Energy Restriction Lowers the Expression of Genes Linked to Inflammation, the Cytoskeleton, the Extracellular Matrix, and Angiogenesis in Mouse Adipose Tissue

2006 · Yoshikazu Higami, Jamie L Barger, et al. · Journal of Nutrition · 126

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

2005 · G. C. Kujoth, A. Hiona, et al. · Science · 2,165

Gene expression profiling studies of aging in cardiac and skeletal muscles

2005 · S PARK, T PROLLA · Cardiovascular Research · 98

Empirical Bayes estimation of gene-specific effects in micro-array research

2004 · Jode W. Edwards, Grier P. Page, et al. · Functional & Integrative Genomics · 8

Statistical methods for testing effects on “maximum lifespan”

2004 · Chenxi Wang, Qing Li, et al. · Mechanisms of Ageing and Development · 208

Impairment of the Transcriptional Responses to Oxidative Stress in the Heart of Aged C57BL/6 Mice

2004 · MICHAEL G. EDWARDS, DEEPAYAN SARKAR, et al. · Annals of the New York Academy of Sciences · 28

The impact of α-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice

2004 · Cheol-Koo Lee, Thomas D Pugh, et al. · Free Radical Biology and Medicine · 134

Novel tumor necrosis factor α–regulated genes in rheumatoid arthritis

2004 · Huang‐Ge Zhang, Karren Hyde, et al. · Arthritis & Rheumatism · 68

Applications of Bayesian Statistical Methods in Microarray Data Analysis

2004 · Dongyan Yang, Stanislav O Zakharkin, et al. · American Journal of PharmacoGenomics · 24

The Evolution of Gene Expression in Mouse Hippocampus in Response to Selective Breeding for Increased Locomotor Activity

2004 · A. M. Bronikowski, J. S. Rhodes, et al. · Evolution · 58

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Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long‐term caloric restriction

2003 · Yoshikazu Higami, Thomas D. Pugh, et al. · The FASEB Journal · 173

The retardation of aging by caloric restriction: its significance in the transgenic era

2003 · Jamie L Barger, Roy L Walford, et al. · Experimental Gerontology · 160

2003 · Michael G. Edwards, Deepayan Sarkar, et al. · Physiological Genomics · 86

Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart

2003 · A. M. Bronikowski, P. A. Carter, et al. · Physiological Genomics · 98

Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

2002 · Cheol-Koo Lee, David B. Allison, et al. · Proceedings of the National Academy of Sciences · 314

Gene Expression Profile of the Aging Brain

2002 · Richard Weindruch, Tomas A. Prolla · Archives of Neurology · 35

Two-Stage Testing in Microarray Analysis: What Is Gained?

2002 · D. B. Allison, C. S. Coffey · The Journals of Gerontology Series A · 18

Effects of Caloric Restriction on Gene Expression

2002 · R. Weindruch, T. Kayo, et al. · KARGER eBooks · 8

Gene expression profiling of aging using DNA microarrays

2002 · Richard Weindruch, Tsuyoshi Kayo, et al. · Mechanisms of Ageing and Development · 171

Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice

2001 · Richard Weindruch, Tsuyoshi Kayo, et al. · Journal of Nutrition · 261

Caloric Intake, Oxidative Stress and Aging

2001 · Cheol Koo Lee, Tomas A. Prolla, et al. · The Scientific World JOURNAL · 4

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Caloric intake, oxidative stress and aging

1998 · R. Weindruch · Pathophysiology · 2

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