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R01 DK-67536

Funded outputs count: 74
Funder award ID: R01 DK-67536
OpenAlex ID: G2910186751
Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors
2025 · Adam C. Swensen, Paul D. Piehowski, et al. · Diabetologia · 6
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Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes
2019 · Prapaporn Jungtrakoon, Jun Shirakawa, et al. · Diabetes · 26
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Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation
2016 · Ivan Achel Valdez, Ercument Dirice, et al. · Cell Reports · 72
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Inhibition of DYRK1A Stimulates Human β-Cell Proliferation
2016 · Ercument Dirice, Deepika Walpita, et al. · Diabetes · 209
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Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia
2016 · Adrian Kee Keong Teo, Hwee Hui Lau, et al. · Stem Cell Reports · 73
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Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas
2016 · Garima Singhal, ffolliott Martin Fisher, et al. · PLoS ONE · 112
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Harnessing Immune Cells to Enhance β-Cell Mass in Type 1 Diabetes
2016 · Ercument Dirice, Rohit N Kulkarni · Journal of Investigative Medicine · 2
Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2)
2015 · Simona S. Ghanem, Garrett Heinrich, et al. · Journal of Biological Chemistry · 8
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SerpinB1 Promotes Pancreatic β Cell Proliferation
2015 · Abdelfattah El Ouaamari, Ercument Dirice, et al. · Cell Metabolism · 234
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β-Cell Glucose Sensitivity Is Linked to Insulin/Glucagon Bihormonal Cells in Nondiabetic Humans
2015 · Teresa Mezza, Gian P. Sorice, et al. · The Journal of Clinical Endocrinology & Metabolism · 49
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Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts
2015 · Manoj K. Gupta, Adrian Kee Keong Teo, et al. · Stem Cells Translational Medicine · 13
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Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes
2015 · Shweta Bhatt, Manoj K. Gupta, et al. · Cell Metabolism · 46
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Human β-Cell Proliferation and Intracellular Signaling: Part 3
2015 · Andrew F. Stewart, Mehboob A. Hussain, et al. · Diabetes · 142
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Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance
2015 · Qusai Y. Al-Share, Anthony M. DeAngelis, et al. · Diabetes · 56
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Cellular stress drives pancreatic plasticity
2015 · Ivan A. Valdez, Adrian K. K. Teo, et al. · Science Translational Medicine · 13
Pancreatic T cell protein–tyrosine phosphatase deficiency affects beta cell function in mice
2014 · Yannan Xi, Siming Liu, et al. · Diabetologia · 23
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Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring
2014 · Sevim Kahraman, Ercument Dirice, et al. · American Journal of Physiology-Endocrinology and Metabolism · 49
Epigenetic modifiers of islet function and mass
2014 · Dario F. De Jesus, Rohit N. Kulkarni · Trends in Endocrinology and Metabolism · 40
The Polycomb protein, Bmi1, regulates insulin sensitivity
2014 · Corey E. Cannon, Paul M. Titchenell, et al. · Molecular Metabolism · 12
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Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum
2014 · Adrian Kee Keong Teo, Ivan Achel Valdez, et al. · Stem Cell Reports · 60
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells
2014 · Chong Wee Liew, Anke Assmann, et al. · Proceedings of the National Academy of Sciences · 45
Palmitate Induces mRNA Translation and Increases ER Protein Load in Islet β-Cells via Activation of the Mammalian Target of Rapamycin Pathway
2014 · Masayuki Hatanaka, Bernhard Maier, et al. · Diabetes · 50
The regulation of pre- and post-maturational plasticity of mammalian islet cell mass
2014 · Teresa Mezza, Rohit N. Kulkarni · Diabetologia · 46
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The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes
2014 · Gamze Kilic, Ana I. Alvarez-Mercado, et al. · PLoS ONE · 50
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Insulin Resistance Alters Islet Morphology in Nondiabetic Humans
2013 · Teresa Mezza, Giovanna Muscogiuri, et al. · Diabetes · 206
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