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Genome-wide Association in Families: Data Integrity, Design and Methods Issue

Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2006-06-15
End date: 2010-11-30
Investigator: JEFFREY R O'CONNELL
Institution: UNIVERSITY OF MARYLAND BALTIMORE
Funded outputs count: 82
Funder award ID: U01HL084756
OpenAlex ID: G3430808022
Correlates of C-reactive protein and its prognostic value for cardiovascular outcomes across the cardiovascular–kidney–metabolic spectrum and PREVENT™ risk: A Cross-Cohort Collaboration study
2026 · Zhiqi Yao, Zeina A. Dardari, et al. · American Journal of Preventive Cardiology
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Association between cigarette smoking status, intensity, and cessation duration with long-term incidence of nine cardiovascular and mortality outcomes: The Cross-Cohort Collaboration (CCC)
2025 · Erfan Tasdighi, Zhiqi Yao, et al. · PLoS Medicine · 25
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Association Between Cigarette Smoking and Subclinical Markers of Cardiovascular Harm
2025 · Zhiqi Yao, Erfan Tasdighi, et al. · Journal of the American College of Cardiology · 29
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease
2023 · Yanhua Chen, Xiaomeng Du, et al. · Nature Genetics · 215
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Insulin resistance and adipose tissue interactions as the cornerstone of metabolic (dysfunction)-associated fatty liver disease pathogenesis
2023 · Shreya C Pal, Nahum Méndez-Sánchez · World Journal of Gastroenterology · 91
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Population‐based meta‐analysis and gene‐set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids
2022 · Samuel K. Handelman, Yindra M. Puentes, et al. · Hepatology Communications · 18
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Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program
2022 · Daniel DiCorpo, Sheila M. Gaynor, et al. · Communications Biology · 22
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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies
2022 · Mathias Gorski, Humaira Rasheed, et al. · Kidney International · 55
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An Amish founder population reveals rare-population genetic determinants of the human lipidome
2022 · May E. Montasser, Stella Aslibekyan, et al. · Communications Biology · 18
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Genomics of Postprandial Lipidomics in the Genetics of Lipid-Lowering Drugs and Diet Network Study
2021 · Marguerite R. Irvin, May E. Montasser, et al. · Nutrients · 4
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Leveraging a founder population to identify novel rare-population genetic determinants of lipidome
2021 · May E. Montasser, Stella Aslibekyan, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Allele-specific variation atAPOEincreases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer’s disease and myocardial infarction
2021 · Nicholette D Palmer, Bratati Kahali, et al. · Human Molecular Genetics · 41
KCNQ1 and Long QT Syndrome in 1/45 Amish
2020 · Elizabeth A. Streeten, Vincent Y. See, et al. · Circulation Genomic and Precision Medicine · 12
A lipidome-wide association study of the lipoprotein insulin resistance index
2020 · Minoo Bagheri, Hemant K. Tiwari, et al. · Lipids in Health and Disease · 11
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Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
2020 · Baier, Leslie J., Hsueh, Wen-Chi, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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Associations of autozygosity with a broad range of human phenotypes
2019 · David W Clark, Yukinori Okada, et al. · Nature Communications · 152
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes
2019 · Llilda Barata, Mary F. Feitosa, et al. · Hepatology Communications · 60
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A fully adjusted two‐stage procedure for rank‐normalization in genetic association studies
2019 · Tamar Sofer, Xiuwen Zheng, et al. · Genetic Epidemiology · 87
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Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology
2017 · Jennifer A Brody, TOPMed Hematology and Hemostasis Working Group, et al. · Nature Genetics · 102
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
2017 · Zillikens, M Carola, Demissie, Serkalem, et al. · MPG.PuRe (Max Planck Society)
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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
2017 · M. Carola Zillikens, Serkalem Demissie, et al. · Nature Communications · 186
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
2017 · Mariaelisa Graff, Robert A. Scott, et al. · PLoS Genetics · 335
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Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis
2017 · Christina G. Tise, Leslie E. Anforth, et al. · Molecular Genetics and Metabolism Reports · 4
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Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation
2016 · Audrey Y Chu, Xuan Deng, et al. · Nature Genetics · 134
Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation
2016 · Shabnam Salimi, Joshua P. Lewis, et al. · Journal of the American Heart Association · 7
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