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DRCNPG-Jun22\\100011

Funded outputs count: 12
Funder award ID: DRCNPG-Jun22\\100011
OpenAlex ID: G3092947936
RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling
2026 · Rosalie Heilig, Hannah Glover, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Thiol Scarcity in Cerebrospinal Fluid Renders Leptomeningeal Acute Lymphoblastic Leukaemia Therapeutically Vulnerable to Ferroptosis
2025 · Nikolai Gajic, Rhona Christie, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Large transient assemblies of Apaf1 constitute the apoptosome in cells
2025 · Alicia C. Borgeaud, Iva Ganeva, et al. · Nature Communications · 8
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Mitochondria and cell death signalling
2025 · Ella Hall-Younger, Stephen WG. Tait · Current Opinion in Cell Biology · 40
Large transient assemblies of Apaf1 constitute the apoptosome in cells
2024 · Alicia C. Borgeaud, Iva Ganeva, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Mitochondria and cell death
2024 · Hannah L. Glover, Annabell Schreiner, et al. · Nature Cell Biology · 473
Getting more bang for their buck: BCL2 inhibitors boost dendritic-cell function to enhance anti-cancer immune surveillance
2024 · Alfredo E. Montes-Gómez, Stephen W. G. Tait · Journal of Translational Medicine · 2
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Tumour immunogenicity goes with the (mitochondrial electron) flow
2024 · Asma Ahmed, Stephen W. G. Tait · Molecular Oncology
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Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis
2024 · Anne von Mässenhausen, Marlena Nastassja Schlecht, et al. · Science Advances · 18
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Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response
2024 · Esmee Vringer, Rosalie Heilig, et al. · The EMBO Journal · 52
Apoptotic stress causes mtDNA release during senescence and drives the SASP
2023 · Stella Victorelli, Hanna Salmonowicz, et al. · Nature · 691
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Sublethal engagement of apoptotic pathways in residual cancer
2023 · Shane T. Killarney, Stephen W.G. Tait, et al. · Trends in Cell Biology · 35
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