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DK-54684

Funded outputs count: 71
Funder award ID: DK-54684
OpenAlex ID: G3104055509
TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective
2016 · Basil Rapoport, Sandra M. McLachlan · Endocrine Reviews · 83
A Unique Mouse Strain That Develops Spontaneous, Iodine-Accelerated, Pathogenic Antibodies to the Human Thyrotrophin Receptor
2015 · Basil Rapoport, Holly A Aliesky, et al. · The Journal of Immunology · 38
Evidence that MHC I-E dampens thyroid autoantibodies and prevents spreading to a second thyroid autoantigen in I-Ak NOD mice
2015 · A-N Pelletier, H A Aliesky, et al. · Genes and Immunity · 10
Graves' Hyperthyroidism Is Antibody-Mediated But Is Predominantly a Th1-Type Cytokine Disease
2014 · Basil Rapoport, Sandra M. McLachlan · The Journal of Clinical Endocrinology & Metabolism · 86
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Sex, Genetics, and the Control of Thyroxine and Thyrotropin in Mice
2014 · Sandra M. McLachlan, Sepehr Hamidi, et al. · Thyroid · 11
Thyroid Autoantibodies Are Rare in Nonhuman Great Apes and Hypothyroidism Cannot Be Attributed to Thyroid Autoimmunity
2013 · Holly Aliesky, Cynthia L. Courtney, et al. · Endocrinology · 27
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Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity
2013 · Sandra M. McLachlan, Basil Rapoport · Endocrine Reviews · 249
Prescience of a Surgeon in 1980
2013 · Sandra M. McLachlan · Thyroid
Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Versa
2012 · Sandra M. McLachlan, Basil Rapoport · Thyroid · 239
The Thyrotropin Receptor Hinge Region as a Surrogate Ligand: Identification of Loci Contributing to the Coupling of Thyrotropin Binding and Receptor Activation
2012 · Chun-Rong Chen, Larry M. Salazar, et al. · Endocrinology · 11
Genetic Linkages for Thyroxine Released in Response to Thyrotropin Stimulation in Three Sets of Recombinant Inbred Mice Provide Evidence for Shared and Novel Genes Controlling Thyroid Function
2012 · Sepehr Hamidi, Holly A. Aliesky, et al. · Thyroid · 5
Breaking Tolerance in Transgenic Mice Expressing the Human TSH Receptor A-Subunit: Thyroiditis, Epitope Spreading and Adjuvant as a ‘Double Edged Sword’
2012 · Sandra M. McLachlan, Holly A. Aliesky, et al. · PLoS ONE · 19
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Role of Self-Tolerance and Chronic Stimulation in the Long-Term Persistence of Adenovirus-Induced Thyrotropin Receptor Antibodies in Wild-Type and Transgenic Mice
2012 · Sandra M. McLachlan, Holly A. Aliesky, et al. · Thyroid · 13
Novel Information on the Epitope of an Inverse Agonist Monoclonal Antibody Provides Insight into the Structure of the TSH Receptor
2012 · Chun-Rong Chen, Larry M. Salazar, et al. · PLoS ONE · 5
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Review and Hypothesis: Does Graves' Disease Develop in Non-Human Great Apes?
2011 · Sandra M. McLachlan, Kristine Alpi, et al. · Thyroid · 27
Exceptional Hyperthyroidism and a Role for both Major Histocompatibility Class I and Class II Genes in a Murine Model of Graves' Disease
2011 · Sandra M. McLachlan, Holly A. Aliesky, et al. · PLoS ONE · 9
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An Attempt to Induce “Graves' Disease of the Gonads” by Immunizing Mice with the Luteinizing Hormone Receptor Provides Insight into Breaking Tolerance to Self-Antigens
2011 · Chun-Rong Chen, Holly A. Aliesky, et al. · Thyroid · 3
Distinct Genetic Signatures for Variability in Total and Free Serum Thyroxine Levels in Four Sets of Recombinant Inbred Mice
2011 · Sandra M. McLachlan, Lu Lu, et al. · Endocrinology · 6
Relationship between Thyrotropin Receptor Hinge Region Proteolytic Posttranslational Modification and Receptor Physiological Function
2010 · Sepehr Hamidi, Chun-Rong Chen, et al. · Molecular Endocrinology · 18
Variable Suppression of Serum Thyroxine in Female Mice of Different Inbred Strains by Triiodothyronine Administered in Drinking Water
2010 · Sepehr Hamidi, Holly Aliesky, et al. · Thyroid · 15
Antibodies to Thyroid Peroxidase Arise Spontaneously with Age in NOD.H-2h4 Mice and Appear after Thyroglobulin Antibodies
2010 · Chun-Rong Chen, Sepehr Hamidi, et al. · Endocrinology · 76
Immunoglobulin heavy chain variable region genes contribute to the induction of thyroid-stimulating antibodies in recombinant inbred mice
2010 · B Rapoport, R W Williams, et al. · Genes and Immunity · 16
Thyrotropin (TSH) Receptor Residue E251 in the Extracellular Leucine-Rich Repeat Domain Is Critical for Linking TSH Binding to Receptor Activation
2010 · Chun-Rong Chen, Sandra M. McLachlan, et al. · Endocrinology · 18
Attenuation of Induced Hyperthyroidism in Mice by Pretreatment with Thyrotropin Receptor Protein: Deviation of Thyroid-Stimulating to Nonfunctional Antibodies
2009 · Alexander V. Misharin, Yuji Nagayama, et al. · Endocrinology · 27
Thyroid Antigens, Not Central Tolerance, Control Responses to Immunization in BALB/c Versus C57BL/6 Mice
2009 · Alexander V. Misharin, Basil Rapoport, et al. · Thyroid · 10
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