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277813

Funded outputs count: 22
Funder award ID: 277813
OpenAlex ID: G314465605
WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome
2022 · Yuyao Tian, Wuming Wang, et al. · Nature Communications · 25
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Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
2022 · Chenglong Xie, Xu-Xu Zhuang, et al. · Nature Biomedical Engineering · 343
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Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations
2021 · Anbin Chen, Cecilie Katrin Kristiansen, et al. · Frontiers in Cell and Developmental Biology · 37
Autophagy in healthy aging and disease
2021 · Yahyah Aman, Tomas Schmauck-Medina, et al. · Nature Aging · 1,314
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Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway
2021 · Yalun Zhang, Yi Zhang, et al. · Brain · 48
DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease
2021 · Heling Wang, Sofie Lautrup, et al. · International Journal of Molecular Sciences · 55
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Re-emphasizing early Alzheimer’s disease pathology starting in select entorhinal neurons, with a special focus on mitophagy
2021 · Asgeir Kobro-Flatmoen, Maria Jose Lagartos-Donate, et al. · Ageing Research Reviews · 121
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Editorial: Mitophagy in Health and Disease
2021 · Konstantinos Palikaras, Evandro Fei Fang, et al. · Frontiers in Cell and Developmental Biology
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Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome
2021 · Ruben Gudmundsrud, Tarjei H. Skjånes, et al. · Cytogenetic and Genome Research · 15
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ARDD 2020: from aging mechanisms to interventions
2020 · Garik V. Mkrtchyan, Kotb Abdelmohsen, et al. · Aging · 58
PharmKG: a dedicated knowledge graph benchmark for bomedical data mining
2020 · Shuangjia Zheng, Jiahua Rao, et al. · Briefings in Bioinformatics · 166
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD + signaling
2020 · Mustafa N. Okur, Evandro F. Fang, et al. · Aging Cell · 52
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A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
2020 · Evandro F. Fang, Chenglong Xie, et al. · Ageing Research Reviews · 681
Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease
2020 · Chenglong Xie, Yahyah Aman, et al. · Frontiers in Cell and Developmental Biology · 30
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Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing
2020 · Brian C. Gilmour, Ruben Gudmundsrud, et al. · Mechanisms of Ageing and Development · 43
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Enhancing mitophagy as a therapeutic approach for neurodegenerative diseases
2020 · Yahyah Aman, Brent Ryan, et al. · International review of neurobiology · 34
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
2019 · Yahyah Aman, Johannes Frank, et al. · Mechanisms of Ageing and Development · 59
NAD+ in Brain Aging and Neurodegenerative Disorders
2019 · Sofie Lautrup, David A. Sinclair, et al. · Cell Metabolism · 789
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Mitophagy and Neuroprotection
2019 · Guofeng Lou, Konstantinos Palikaras, et al. · Trends in Molecular Medicine · 456
Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease
2019 · Sofie Lautrup, Guofeng Lou, et al. · Neurochemistry International · 105
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Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases
2019 · Sofie Lautrup, Domenica Caponio, et al. · Biogerontology · 36
Therapeutic potential of boosting NAD+ in aging and age-related diseases
2018 · Yahyah Aman, Yumin Qiu, et al. · Translational Medicine of Aging · 84
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