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R01-HL-092961

Funded outputs count: 59
Funder award ID: R01-HL-092961
OpenAlex ID: G3154139807
Modulation of an aberrant basal cell program in human alveolar epithelial spheroids and lung slices
2025 · Yong Li, Jack H. Wellmerling, et al. · Respiratory Research · 3
Optimized Synthetic Flavonols Support Senescence Clearance and Lung Fibrosis Resolution
2025 · Jeffrey A. Meridew, John A. Vu, et al. · ACS Pharmacology & Translational Science · 2
Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer
2025 · Taslim A. Al-Hilal, Maria-Anna Chrysovergi, et al. · Nature Cell Biology · 36
Vascular protection by young circulating extracellular vesicles ameliorates aging-related pulmonary fibrosis
2025 · Fiorenza Gianì, Benjamin B. Roos, et al. · American Journal of Physiology-Cell Physiology · 6
Targeting CEBPA to restore cellular identity and tissue homeostasis in pulmonary fibrosis
2024 · Qi Tan, Jack H. Wellmerling, et al. · JCI Insight · 14
A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung
2024 · Patrick A. Link, Jeffrey A. Meridew, et al. · American Journal of Respiratory Cell and Molecular Biology · 3
RNA ‐sequencing reveals differential fibroblast responses to bleomycin and pneumonectomy
2024 · Jack H Wellmerling, Sara R Dresler, et al. · Physiological Reports · 1
Defining signals that promote human alveolar type I differentiation
2024 · Yong Li, Y. S. Prakash, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 9
Dopamine Receptor D1 Is Exempt from Transforming Growth Factor β-Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts
2023 · Ashley Y. Gao, Ana M. Diaz Espinosa, et al. · Journal of Pharmacology and Experimental Therapeutics · 15
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The matricellular protein CCN3 supports lung endothelial homeostasis and function
2022 · Kalpana R. Betageri, Patrick A. Link, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 14
Pim-1 kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome
2022 · Ashley Y. Gao, Ana M. Diaz Espinosa, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 15
Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis
2022 · Nunzia Caporarello, Jisu Lee, et al. · Nature Communications · 94
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Transcriptional analysis of lung fibroblasts identifies PIM1 signaling as a driver of aging-associated persistent fibrosis
2022 · Tho X. Pham, Jisu Lee, et al. · JCI Insight · 48
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Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis
2021 · Enis Kostallari, Bo Wei, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 70
Combined control of the fibroblast contractile program by YAP and TAZ
2021 · Patrick A. Link, Kyoung Moo Choi, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 45
GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
2021 · Kyoung Moo Choi, Andrew J. Haak, et al. · Journal of Cellular Physiology · 32
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation
2021 · Dakota L. Jones, Jeffrey A. Meridew, et al. · The Journal of Cell Biology · 42
Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators
2021 · Qi Tan, Patrick A. Link, et al. · American Journal of Respiratory Cell and Molecular Biology · 49
Dopamine D1 receptor stimulates cathepsin K-dependent degradation and resorption of collagen I in lung fibroblasts
2020 · Ana M. Diaz Espinosa, Patrick A. Link, et al. · Journal of Cell Science · 25
Vascular dysfunction in aged mice contributes to persistent lung fibrosis
2020 · Nunzia Caporarello, Jeffrey A. Meridew, et al. · Aging Cell · 82
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Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma
2020 · Daniel J. Tschumperlin, David Lagares · Pharmacology & Therapeutics · 147
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation
2020 · Aja Aravamudhan, Andrew J. Haak, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 42
Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies
2020 · Andrew J. Haak, Merrick T. Ducharme, et al. · Trends in Pharmacological Sciences · 69
Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression
2019 · Wei Liu, Jeffrey A. Meridew, et al. · Respiratory Research · 26
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Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis
2019 · Jeffrey C. Horowitz, Daniel J. Tschumperlin, et al. · Thrombosis and Haemostasis · 29
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