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Caloric Restriction and Aging in Humans

Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2001-09-30
End date: 2009-09-29
Investigator: JOHN O. HOLLOSZY
Institution: WASHINGTON UNIVERSITY
Funded outputs count: 70
Funder award ID: U01AG020487
OpenAlex ID: G1901358732
Biological Pathways of Strength Preservation During Calorie Restriction‐Induced Weight Loss Among Adults Without Obesity
2026 · Nadia Moore, Akshay Bareja, et al. · Obesity
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Self-selected dietary intake and association with achieved caloric restriction in CALERIE ™ 2
2026 · Emily K. Woolf, Kaja Falkenhain, et al. · Critical Reviews in Food Science and Nutrition
Metabolic Adaptations to Caloric Restriction: Time- and Group-Dependent Metabolomic Signatures from the CALERIE™ Trial
2026 · Melissa C. Orenduff, Emily K. Woolf, et al. · Research Square
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Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial
2026 · Jayanta K. Das, Yu Zhang, et al. · GeroScience
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Use of Machine Learning to Identify Determinants of Habitual-Preformed Water Intake
2026 · Emma J Stinson, Ethan Collins, et al. · Journal of Nutrition
Effect of 2-Year Caloric Restriction in the Absence of Malnutrition on Indicators of Anemia, Iron Status, and Hepcidin in Healthy Adults: A Randomized Clinical Trial
2026 · Cory Dugan, Sai Krupa Das, et al. · Journal of Nutrition · 1
Biological Mechanisms of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Young- to Middle-Aged Adults without Obesity
2026 · Nadia Moore, Akshay Bareja, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Diet quality and nutritional adequacy during a 2-year calorie restriction intervention: the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy 2 trial
2025 · Susan B Racette, Rachel E Silver, et al. · American Journal of Clinical Nutrition · 3
Association between physical activity energy expenditure and markers of healthspan during prolonged calorie restriction in individuals without obesity: observations from the CALERIE™ phase 2 randomized controlled trial
2025 · James L. Dorling, Corby K. Martin, et al. · International Journal of Behavioral Nutrition and Physical Activity · 2
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A 2-year calorie restriction intervention may reduce glycomic biological age biomarkers – a pilot study
2025 · Tea Pribić, Jayanta K. Das, et al. · npj Aging · 11
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Increasing the health span: unique role for exercise
2025 · Glenn A. Gaesser, Stephanie E. Hall, et al. · Journal of Applied Physiology · 18
The effect of a leptin phenotype on weight change and energy expenditure responses to acute and prolonged energetic stressors
2025 · Kaja Falkenhain, Tomás Cabeza De Baca, et al. · American Journal of Physiology-Endocrinology and Metabolism · 2
A 2-year calorie restriction intervention reduces glycomic biological age biomarkers
2024 · Tea Pribić, Jayanta K Das, et al. · medRxiv · 1
Prediction of individual weight loss using supervised learning: findings from the CALERIETM 2 study
2024 · Christina Glasbrenner, Christoph Höchsmann, et al. · American Journal of Clinical Nutrition · 8
Effect of long‐term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis
2024 · Waylon J. Hastings, Qiaofeng Ye, et al. · Aging Cell · 36
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Calorie restriction reduces biomarkers of cellular senescence in humans
2023 · Zaira Aversa, Thomas A. White, et al. · Aging Cell · 65
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Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study
2023 · Jayanta Kumar Das, Nirad Banskota, et al. · Aging Cell · 71
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Proportion of caloric restriction‐induced weight loss as skeletal muscle
2023 · Steven B. Heymsfield, Shengping Yang, et al. · Obesity · 53
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Body shape perception in men and women without obesity during caloric restriction: a secondary analysis from the CALERIE study
2023 · Maci M. Jacobson, Alexis M. Gardner, et al. · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · 2
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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging
2022 · Seungjin Ryu, Sviatoslav Sidorov, et al. · Immunity · 123
Nutritional quality of calorie restricted diets in the CALERIE™ 1 trial
2022 · Susan B. Racette, Valene Garr Barry, et al. · Experimental Gerontology · 3
Associations between the timing of eating and weight-loss in calorically restricted healthy adults: Findings from the CALERIE study
2022 · Jason G. Fleischer, Sai Krupa Das, et al. · Experimental Gerontology · 27
Challenges in defining successful adherence to calorie restriction goals in humans: Results from CALERIE™ 2
2022 · Corby K. Martin, Christoph Höchsmann, et al. · Experimental Gerontology · 19
Caloric restriction in humans reveals immunometabolic regulators of health span
2022 · O. Spadaro, Y. Youm, et al. · Science · 317
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Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial
2022 · Kim M. Huffman, Daniel C. Parker, et al. · EClinicalMedicine · 83
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