Award

Endogenous Repair

Description: Every two minutes one Canadian over the age of 65 will experience a fall-related injury. Frequently this results in hospitalization, loss of independence, or in some cases, death. The goal of the proposed CRC research program is to develop therapeutics that increase muscle strength after injury as a strategy to overcome a risk factor of senior falls. To achieve this goal, Dr. Gilbert will use hypothesis-driven research to identify molecules that target and rejuvenate muscle stem cells within aging skeletal muscle. These efforts will be supported by inventing a miniaturized human skeletal muscle tissue model of aging for hypothesis testing.

Funder: Natural Sciences and Engineering Research Council of Canada

Amount: CA$100,000

Funding type: research

Funder scheme: Canada Research Chairs

Start date: 2023-04-01

End date: 2024-03-31

Investigator: Penney Gilbert

Institution: University of Toronto

Topic: Muscle Physiology and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Funded outputs count: 0

Funder award ID: crc-2020-00278

OpenAlex ID: G3201845699