Award

Mechanisms of Ischemic Kidney Injury and Repair

Description: The work proposed in this application is designed to understand how injury to the kidney results in abnormal repair leading to long term kidney dysfunction and ultimately failure of the organ to support life. Approximately 9% of the developed world's adult population has chronic kidney disease and there are currently no effective therapies to prevent progression of the disease once it is established. Our work is designed to better understand the factors in the kidney that are responsible for progressive disease so that we can develop new therapies to prevent the progression and the side effects of kidney disease.
Funding type: research
Funder scheme: R37
Start date: 1984-09-01
End date: 2023-12-19
Investigator: JOSEPH VINCENT BONVENTRE
Institution: BRIGHAM AND WOMEN'S HOSPITAL
Funded outputs count: 227
Funder award ID: R37DK039773
OpenAlex ID: G1591357002
2025 · Christina L. Tamargo, Steven G. Coca, et al. · JCI Insight · 11
2025 · Clara Steiner, Marc Machaalani, et al. · European Urology Focus · 14
2025 · Samuel Mon-Wei Yu, John Yongjoon Choi, et al. · Kidney International · 3
2025 · Jason H. Greenberg, Alison G. Abraham, et al. · Journal of the American Society of Nephrology · 11
2024 · SoonGweon Hong, Minsun Song, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
2024 · Teresa K. Chen, Michelle M. Estrella, et al. · Clinical Journal of the American Society of Nephrology · 5
2024 · Lipika Samal, John L. Kilgallon, et al. · JAMA Internal Medicine · 33
2024 · Pierre Galichon, Morgane Lannoy, et al. · American Journal of Physiology-Renal Physiology · 12
2024 · Bryan A. Nerger, Sumit Sinha, et al. · Advanced Materials · 82
2024 · William A. Anderson, Arce Domingo-Relloso, et al. · Environmental Research · 11
2023 · Arthur M. Lee, Yunwen Xu, et al. · Clinical Journal of the American Society of Nephrology · 16
2023 · Elizabeth A. Kiernan, David Hu, et al. · American Journal of Kidney Diseases · 8
2023 · George Vasquez-Rios, Ronit Katz, et al. · Kidney360 · 13
2023 · Thomas Plum, Rebecca Binzberger, et al. · Nature · 131
2023 · Eoin D. O’Sullivan, Katie J. Mylonas, et al. · Science Translational Medicine · 49
2023 · Nicholas Wettersten, Ronit Katz, et al. · The American Journal of Cardiology · 6
2023 · Jaime M. Restrepo, Laura Torres-Canchala, et al. · Frontiers in Pediatrics · 2
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