Adult Changes in Thought (ACT) Research Program
Description: This proposal seeks to improve understanding of aging, brain aging and dementia specifically by expanding, modernizing and improving a longstanding cohort study of older adults enrolled from a healthcare delivery system with extensive records from clinical care. The Adult Changes in Thought (ACT) U19 Research Program has identified incident cases of dementia (>1,300 to date) and Alzheimer's disease (>1,000 to date) and follows consenting participants to autopsy (>850 to date). The U19 Program will provide valuable data on extremely well characterized individuals and aims to identify targets for prevention and treatment of Alzheimer's disease and other age-related disorders and facilitate greater collaborative research by expanding and improving dissemination of our exceptional resources.
Funder: National Institute on Aging
Funding type: cooperative_agreement
Funder scheme: U19
Start date: 2021-05-15
End date: 2026-06-30
Investigator: PAUL K CRANE
Institution: KAISER FOUNDATION RESEARCH INSTITUTE
Funded outputs count: 240
Funder award ID: U19AG066567
OpenAlex ID: G9000872788