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RC2-DK088389

Funded outputs count: 22
Funder award ID: RC2-DK088389
OpenAlex ID: G328833407
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
2019 · Broad Genomics Platform, Jason Flannick, et al. · Nature · 303
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Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution
2017 · Reedik Mägi, Momoko Horikoshi, et al. · Human Molecular Genetics · 279
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An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
2017 · Robert A. Scott, Laura J. Scott, et al. · Diabetes · 736
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
2017 · Alisa Manning, Heather M. Highland, et al. · Diabetes · 50
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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
2016 · Praveen Surendran, Lifelines Cohort Study, et al. · Nature Genetics · 311
A reference panel of 64,976 haplotypes for genotype imputation
2016 · Shane McCarthy, Yang Luo, et al. · Nature Genetics · 2,833
Analysis of protein-coding genetic variation in 60,706 humans
2016 · Monkol Lek, Konrad J. Karczewski, et al. · Nature · 9,586
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The genetic architecture of type 2 diabetes
2016 · Christian Fuchsberger, Jason Flannick, et al. · Nature · 1,049
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An efficient resampling method for calibrating single and gene-based rare variant association analysis in case–control studies
2015 · Seunggeun Lee, Christian Fuchsberger, et al. · Biostatistics · 52
The Power of Gene-Based Rare Variant Methods to Detect Disease-Associated Variation and Test Hypotheses About Complex Disease
2015 · Loukas Moutsianas, Vineeta Agarwala, et al. · PLoS Genetics · 129
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Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
2015 · Anubha Mahajan, Xueling Sim, et al. · PLoS Genetics · 110
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
2014 · Siddhartha Jaiswal, Pierre Fontanillas, et al. · New England Journal of Medicine · 4,821
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Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
2014 · Amit R. Majithia, Jason Flannick, et al. · Proceedings of the National Academy of Sciences · 171
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Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
2014 · Elaine T. Lim, Peter Würtz, et al. · PLoS Genetics · 49
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Simulation of Finnish Population History, Guided by Empirical Genetic Data, to Assess Power of Rare-Variant Tests in Finland
2014 · Sophie R. Wang, Vineeta Agarwala, et al. · The American Journal of Human Genetics · 22
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Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
2014 · Jason Flannick, Gudmar Thorleifsson, et al. · Nature Genetics · 489
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
2014 · Lim E.T., Würtz P., et al. · Digital Commons@Becker (Washington University School of Medicine) · 387
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Evaluating empirical bounds on complex disease genetic architecture
2013 · Vineeta Agarwala, Jason Flannick, et al. · Nature Genetics · 143
Assessing association between protein truncating variants and quantitative traits
2013 · Manuel A. Rivas, Matti Pirinen, et al. · Bioinformatics · 18
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Recommended Joint and Meta‐Analysis Strategies for Case‐Control Association Testing of Single Low‐Count Variants
2013 · Clement Ma, Tom Blackwell, et al. · Genetic Epidemiology · 155
What Will Diabetes Genomes Tell Us?
2012 · Karen L. Mohlke, Laura J. Scott · Current Diabetes Reports · 10
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Detection of cis-acting regulatory SNPs using allelic expression data
2011 · Rui Xiao, Laura J. Scott · Genetic Epidemiology · 18
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